Braided endovascular implants for intracranial aneurysms: mechanics, hemodynamics, and clinical translation
Abstract
Endovascular implants prevent intracranial aneurysm rupture by altering the mechanical and hemodynamic environment at the aneurysm neck. Yet many in silico workflows prescribe or reconstruct the post-deployment geometry before computing flow, leaving unresolved the mechanics that create the clinically relevant interface. Here we review braided intraluminal flow diverters, intrasaccular devices, and emerging flow-disruption concepts across deployment mechanics, inter-wire and wire-wall contact, superelasticity, wall apposition, pore geometry, computational fluid dynamics, and fluid-structure interaction. We connect these modeling choices to neck coverage, malapposition, migration, deformation, and durability, and distinguish established evidence from mechanistic inference and prospective hypotheses. We argue that model fidelity should match the clinical question: prescribed or fast placement may support screening, whereas questions of coverage, apposition, compaction, and migration benefit from mechanically plausible deployment states. An interface-resolved mechanics-to-flow framework, supported by measurable validation targets and standardized reporting, could improve device design and enable more reliable patient-specific treatment planning.
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BibTeX
@misc{pramanik2026braided,
title = {{Braided endovascular implants for intracranial aneurysms: mechanics, hemodynamics, and clinical translation}},
author = {Ratnadeep Pramanik and Duygu Dengiz and Mariya S. Pravdivtseva and Martin Frank and Ivo Steinbrecher and Prasanth Velvaluri and Matthias Mayr and Philipp Berg and Sylvia Saalfeld and Naomi Larsen and Olav Jansen and Alexander Popp},
howpublished = {arXiv},
year = {2026},
month = oct,
doi = {10.48550/arxiv.2609.18544},
eprint = {2609.18544},
archivePrefix = {arXiv},
url = {https://arxiv.org/abs/2609.18544},
}
RIS
TY - UNPB
TI - Braided endovascular implants for intracranial aneurysms: mechanics, hemodynamics, and clinical translation
AU - Ratnadeep Pramanik
AU - Duygu Dengiz
AU - Mariya S. Pravdivtseva
AU - Martin Frank
AU - Ivo Steinbrecher
AU - Prasanth Velvaluri
AU - Matthias Mayr
AU - Philipp Berg
AU - Sylvia Saalfeld
AU - Naomi Larsen
AU - Olav Jansen
AU - Alexander Popp
PY - 2026
DA - 2026/10/15
PB - arXiv
DO - 10.48550/arxiv.2609.18544
UR - https://arxiv.org/abs/2609.18544
AB - Endovascular implants prevent intracranial aneurysm rupture by altering the mechanical and hemodynamic environment at the aneurysm neck. Yet many in silico workflows prescribe or reconstruct the post-deployment geometry before computing flow, leaving unresolved the mechanics that create the clinically relevant interface. Here we review braided intraluminal flow diverters, intrasaccular devices, and emerging flow-disruption concepts across deployment mechanics, inter-wire and wire-wall contact, superelasticity, wall apposition, pore geometry, computational fluid dynamics, and fluid-structure interaction. We connect these modeling choices to neck coverage, malapposition, migration, deformation, and durability, and distinguish established evidence from mechanistic inference and prospective hypotheses. We argue that model fidelity should match the clinical question: prescribed or fast placement may support screening, whereas questions of coverage, apposition, compaction, and migration benefit from mechanically plausible deployment states. An interface-resolved mechanics-to-flow framework, supported by measurable validation targets and standardized reporting, could improve device design and enable more reliable patient-specific treatment planning.
ER -