Establishment of new energy supply construction inspired by the defensive mechanism of Pheropsophus occipitalis
- 1School of Life Science, Anhui University , , ,
- 2State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences , ,
- 3School of Biotechnology, Jiangnan University , ,
Abstract
The defensive chemical system of Pheropsophus occipitalis has long been a research focus on biomimetic catalysis and energy applications, yet the biosynthetic origin of hydrogen peroxide (H2O2) in its defensive glands remains unresolved. This work aimed to decipher the underlying catalytic mechanism and develop a novel biomimetic energy supply strategy. Electron paramagnetic resonance (EPR) spectroscopy and molecular docking were employed to verify the radical-mediated pathway of laccase-catalyzed hydroquinone oxidation. Laccase and catalase were co-immobilized on cerium oxide–titanium dioxide composite supports to enhance catalytic stability and efficiency. A biomimetic microchannel catalyst bed coupled with a pulsed cascade booster system was further constructed, inspired by the compartmentalized anatomy of P. occipitalis. We demonstrate for the first time that laccase catalyzes hydroquinone oxidation to generate H2O2 via radical intermediates, and reveal a triple synergistic catalytic cycle consisting of oxygen regeneration, hydrogen element turnover, and cerium redox shuttle. The immobilized laccase yields a relative H2O2 concentration of 191.79%, corresponding to a 9.2-fold improvement over free laccase. The integrated biomimetic system realizes on-demand in situ generation and utilization of H2O2. This study advances the mechanistic understanding of the P. occipitalis chemical defense system, and provides a novel, low-noise and eco-friendly technical route for the development of portable energy supply systems.
Related
- Construction and mechanism of histone deacetylation related gene prognosis model in esophageal carcinoma
- Viscoelastic liquid lassos extend the defensive reach of termite soldiers
- Establishment of a Three-Dimensional In Vitro Model of Taste Bud Cells for Fat Taste Investigation
- Effects of different disinfectants and culture substrates on aseptic germination and aseptic seedling establishment of Cajanus cajan (L.) Millsp
- Distinct Phases of Postnatal Skeletal Muscle Growth Govern the Progressive Establishment of Muscle Stem Cell Quiescence
BibTeX
@article{wang2026establishment,
title = {{Establishment of new energy supply construction inspired by the defensive mechanism of Pheropsophus occipitalis}},
author = {Lin Wang and Yun Zhang and Fanghan Che and Xinyi Yao and Jiajun Yu and Weiping Li and Ruoshui Wang and Ruochun Yin},
journal = {Frontiers in chemistry},
year = {2026},
month = oct,
doi = {10.3389/fchem.2026.1831087},
url = {https://europepmc.org/article/PMC/PMC13729060},
note = {CC BY},
}
RIS
TY - JOUR
TI - Establishment of new energy supply construction inspired by the defensive mechanism of Pheropsophus occipitalis
AU - Lin Wang
AU - Yun Zhang
AU - Fanghan Che
AU - Xinyi Yao
AU - Jiajun Yu
AU - Weiping Li
AU - Ruoshui Wang
AU - Ruochun Yin
PY - 2026
DA - 2026/10/20
JO - Frontiers in chemistry
DO - 10.3389/fchem.2026.1831087
UR - https://europepmc.org/article/PMC/PMC13729060
AB - The defensive chemical system of Pheropsophus occipitalis has long been a research focus on biomimetic catalysis and energy applications, yet the biosynthetic origin of hydrogen peroxide (H2O2) in its defensive glands remains unresolved. This work aimed to decipher the underlying catalytic mechanism and develop a novel biomimetic energy supply strategy. Electron paramagnetic resonance (EPR) spectroscopy and molecular docking were employed to verify the radical-mediated pathway of laccase-catalyzed hydroquinone oxidation. Laccase and catalase were co-immobilized on cerium oxide–titanium dioxide composite supports to enhance catalytic stability and efficiency. A biomimetic microchannel catalyst bed coupled with a pulsed cascade booster system was further constructed, inspired by the compartmentalized anatomy of P. occipitalis. We demonstrate for the first time that laccase catalyzes hydroquinone oxidation to generate H2O2 via radical intermediates, and reveal a triple synergistic catalytic cycle consisting of oxygen regeneration, hydrogen element turnover, and cerium redox shuttle. The immobilized laccase yields a relative H2O2 concentration of 191.79%, corresponding to a 9.2-fold improvement over free laccase. The integrated biomimetic system realizes on-demand in situ generation and utilization of H2O2. This study advances the mechanistic understanding of the P. occipitalis chemical defense system, and provides a novel, low-noise and eco-friendly technical route for the development of portable energy supply systems.
SN - 2296-2646
ER -