Cannabis use patterns, depression trajectories and suicide attempts: a 10-year longitudinal study
Abstract
Cannabis use has been consistently associated with increased risks of depression, suicidal ideation, and suicide attempt. We aimed to compare the trajectories of depression and suicide attempt risk among individuals who used cannabis before or concomitantly with the onset of depressive symptoms, relative to depressed individuals who did not use cannabis. We used data from 24,446 participants of CONSTANCES, a French national cohort, recruited between 2013 to 2020. People who started using cannabis before the onset of a depressive episode showed shorter durations of depression, and were half as likely to attempt suicide than the general depressed population. On the other hand, people with concomitant onset of cannabis use and depression showed similar characteristics compared to the general depressed population. These findings suggest that specific patterns of cannabis use could be linked to a lower risk of adverse mental health outcomes.
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BibTeX
@article{maviel2026cannabis,
title = {{Cannabis use patterns, depression trajectories and suicide attempts: a 10-year longitudinal study}},
author = {Gustave Maffre Maviel and Camille Davisse-Paturet and Antoine Duclos and Emmanuel Wiernik and Guillaume Airagnes and Maria Melchior},
journal = {Translational Psychiatry},
year = {2026},
month = aug,
doi = {10.1038/s41398-026-04344-4},
url = {https://hal.science/hal-05760998v1},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - JOUR
TI - Cannabis use patterns, depression trajectories and suicide attempts: a 10-year longitudinal study
AU - Gustave Maffre Maviel
AU - Camille Davisse-Paturet
AU - Antoine Duclos
AU - Emmanuel Wiernik
AU - Guillaume Airagnes
AU - Maria Melchior
PY - 2026
DA - 2026/08/11
JO - Translational Psychiatry
DO - 10.1038/s41398-026-04344-4
UR - https://hal.science/hal-05760998v1
AB - Cannabis use has been consistently associated with increased risks of depression, suicidal ideation, and suicide attempt. We aimed to compare the trajectories of depression and suicide attempt risk among individuals who used cannabis before or concomitantly with the onset of depressive symptoms, relative to depressed individuals who did not use cannabis. We used data from 24,446 participants of CONSTANCES, a French national cohort, recruited between 2013 to 2020. People who started using cannabis before the onset of a depressive episode showed shorter durations of depression, and were half as likely to attempt suicide than the general depressed population. On the other hand, people with concomitant onset of cannabis use and depression showed similar characteristics compared to the general depressed population. These findings suggest that specific patterns of cannabis use could be linked to a lower risk of adverse mental health outcomes.
SN - 2158-3188
SN - 2158-3188
ER -