A new La-complex immobilized on GO Ni-MNC nanocomposite as a green, returnable, robust and homoselective nanocatalyst in the synthesis of biological organic compounds
- 1Department of Chemistry, Faculty of Science, Ilam University P. O. Box 69315516 Ilam Iran
Abstract
In this work, graphene oxide (GO) was formed via a modified Hummers' method. Then, a magnetic graphene oxide nanocomposite (GO Ni-MNC) was prepared by magnetizing GO with magnetic nickel nanoparticles (Ni-MNPs). Then, the surface of GO Ni-MNC was modified using 3-iodopropyltrimethoxysilane (3-IPTMS). Then, a new lanthanum complex of (3-pyridin-3-ylmethyl)2thiourea was anchored on the surface of modified GO Ni-MNC, which was labeled as La-PMTU@GO Ni-MNC. This nanocatalyst was characterized by SEM, EDS, WDX, XRD, FT-IR, BET and VSM techniques. La-PMTU@GO Ni-MNC was investigated as a new, highly effective, reusable and homoselective nanocatalyst for the synthesis of tetrahydrobenzo [b]pyrans and pyranopyrazoles through multicomponent reactions. The homoselectivity of this catalyst was confirmed by NMR spectroscopy. Two examples of pyranopyrazole compounds that have anticancer and ChK1 inhibitor properties were synthesized with high efficiency and purity in this work. This La-PMTU@GO Ni-MNC catalyst showed good reusability for up to four runs without meaningful loss of catalytic performance. The lanthanum leaching and heterogeneous nature of the La-PMTU@GO Ni-MNC nanocatalyst was investigated by ICP-OES analysis. The La-PMTU@GO Ni-MNC nanocatalyst was recovered and reused over six consecutive cycles, and the recovered catalyst was characterized using FT-IR, EDS, WDX, and SEM techniques.
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BibTeX
@article{tahmasbi2026lacomplex,
title = {{A new La-complex immobilized on GO Ni-MNC nanocomposite as a green, returnable, robust and homoselective nanocatalyst in the synthesis of biological organic compounds}},
author = {Bahman Tahmasbi and Sadeq Abdulhasan Mohammed Al-Juhaishi and Mitra Darabi and Omid Soleimani},
journal = {RSC advances},
year = {2026},
month = oct,
doi = {10.1039/d6ra09926b},
url = {https://europepmc.org/article/PMC/PMC13701150},
note = {CC BY},
}
RIS
TY - JOUR
TI - A new La-complex immobilized on GO Ni-MNC nanocomposite as a green, returnable, robust and homoselective nanocatalyst in the synthesis of biological organic compounds
AU - Bahman Tahmasbi
AU - Sadeq Abdulhasan Mohammed Al-Juhaishi
AU - Mitra Darabi
AU - Omid Soleimani
PY - 2026
DA - 2026/10/26
JO - RSC advances
DO - 10.1039/d6ra09926b
UR - https://europepmc.org/article/PMC/PMC13701150
AB - In this work, graphene oxide (GO) was formed via a modified Hummers' method. Then, a magnetic graphene oxide nanocomposite (GO Ni-MNC) was prepared by magnetizing GO with magnetic nickel nanoparticles (Ni-MNPs). Then, the surface of GO Ni-MNC was modified using 3-iodopropyltrimethoxysilane (3-IPTMS). Then, a new lanthanum complex of (3-pyridin-3-ylmethyl)2thiourea was anchored on the surface of modified GO Ni-MNC, which was labeled as La-PMTU@GO Ni-MNC. This nanocatalyst was characterized by SEM, EDS, WDX, XRD, FT-IR, BET and VSM techniques. La-PMTU@GO Ni-MNC was investigated as a new, highly effective, reusable and homoselective nanocatalyst for the synthesis of tetrahydrobenzo [b]pyrans and pyranopyrazoles through multicomponent reactions. The homoselectivity of this catalyst was confirmed by NMR spectroscopy. Two examples of pyranopyrazole compounds that have anticancer and ChK1 inhibitor properties were synthesized with high efficiency and purity in this work. This La-PMTU@GO Ni-MNC catalyst showed good reusability for up to four runs without meaningful loss of catalytic performance. The lanthanum leaching and heterogeneous nature of the La-PMTU@GO Ni-MNC nanocatalyst was investigated by ICP-OES analysis. The La-PMTU@GO Ni-MNC nanocatalyst was recovered and reused over six consecutive cycles, and the recovered catalyst was characterized using FT-IR, EDS, WDX, and SEM techniques.
SN - 2046-2069
ER -