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Peer-reviewedCC BYClinical case reports

Adrenalectomy for a Large Non-Functional Adrenocortical Tumor With Aggressive Histopathologic Features: A Clinical Case Report.

  • Jawad Khan1
  • Abdul Eizad Asif2
  • Hammad Yousaf2
  • Haider Ali Nawaz3
  • Muhammad Hassaan2
  • Samiya Rahim1
  • Farzana Yeasmin4
  • Muddassir Khalid5
  • Fred Segawa6
6 affiliations
  1. 1Department of Urology Ayub Teaching Hospital Abbottabad Khyber Pakhtunkhwa Pakistan.
  2. 2Department of Internal Medicine Shalamar Medical and Dental College Lahore Punjab Pakistan.
  3. 3Department of Internal Medicine Allama Iqbal Medical College Lahore Punjab Pakistan.
  4. 4Shaheed Suhrawardy Medical College Dhaka Bangladesh.
  5. 5Department of Medicine Nishtar Medical University Multan Punjab Pakistan.
  6. 6Department of Medicine Makerere University College of Health Sciences Kampala Central Region Uganda.
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Abstract

Adrenocortical tumors are infrequent neoplasms, ranging from benign adenomas to aggressive carcinomas. They usually have an unspecific clinical presentation, thus being a challenge in diagnosis and treatment. The following case report discusses the management of a large, non-functional adrenocortical tumor with histologically aggressive features, underlining the diagnostic workup, the multidisciplinary surgical approach, and the short-term postoperative outcome after adrenalectomy. We report the case of a 40-year-old female patient presenting with dull left flank pain and a large, non-functional adrenal mass. She underwent open left adrenalectomy. The resected specimen measured 8.4 × 7.6 × 6.5 cm and was histopathologically diagnosed as adrenocortical carcinoma. She was discharged on the 4th post-operative day and at the 3-month follow-up was found to be disease-free on imaging.

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Cite

BibTeXRIS
BibTeX
@article{khan2026adrenalectomy,
  title = {{Adrenalectomy for a Large Non-Functional Adrenocortical Tumor With Aggressive Histopathologic Features: A Clinical Case Report.}},
  author = {Jawad Khan and Abdul Eizad Asif and Hammad Yousaf and Haider Ali Nawaz and Muhammad Hassaan and Samiya Rahim and Farzana Yeasmin and Muddassir Khalid and Fred Segawa},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73740},
  url = {https://europepmc.org/article/MED/42921484},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Adrenalectomy for a Large Non-Functional Adrenocortical Tumor With Aggressive Histopathologic Features: A Clinical Case Report.
AU  - Jawad Khan
AU  - Abdul Eizad Asif
AU  - Hammad Yousaf
AU  - Haider Ali Nawaz
AU  - Muhammad Hassaan
AU  - Samiya Rahim
AU  - Farzana Yeasmin
AU  - Muddassir Khalid
AU  - Fred Segawa
PY  - 2026
DA  - 2026/10/23
JO  - Clinical case reports
DO  - 10.1002/ccr3.73740
UR  - https://europepmc.org/article/MED/42921484
AB  - Adrenocortical tumors are infrequent neoplasms, ranging from benign adenomas to aggressive carcinomas. They usually have an unspecific clinical presentation, thus being a challenge in diagnosis and treatment. The following case report discusses the management of a large, non-functional adrenocortical tumor with histologically aggressive features, underlining the diagnostic workup, the multidisciplinary surgical approach, and the short-term postoperative outcome after adrenalectomy. We report the case of a 40-year-old female patient presenting with dull left flank pain and a large, non-functional adrenal mass. She underwent open left adrenalectomy. The resected specimen measured 8.4 × 7.6 × 6.5 cm and was histopathologically diagnosed as adrenocortical carcinoma. She was discharged on the 4th post-operative day and at the 3-month follow-up was found to be disease-free on imaging.
SN  - 2050-0904
ER  -