Near-complete telomere-to-telomere genome assembly of a male barbel steed (Hemibarbus labeo)
- 1Zhejiang Fisheries Technical Extension Center, Hangzhou, 310023 China
Abstract
The barbel steed (Hemibarbus labeo), an economically important freshwater fish in China, belongs to the order Cypriniformes and the family Cyprinidae. At present, research has been conducted on the basic biology, artificial breeding, aquaculture, and nutritional requirements of H. labeo. However, genome assembly and exploration of the unique genomic composition of the barbel steed are still in their infancy. Previously available genome assemblies were fragmented and incomplete, hindering advances in genomic research and breeding applications. In this study, we generated a near complete telomere-to-telomere (T2T) genome assemblies for a male H. labeo using PacBio HiFi, ONT ultra-long, and Hi-C data. The resulting assemblies span 1,040.46 Mb with contig N50 of 41.15 Mb, and 25 chromosomes were assembled. The quality value (QV) scores were 60.02, and Benchmarking Universal Single-Copy Orthologs (BUSCO) completeness scores were 98.3%. The genome contains a total of 37,023 coding genes, of which 35,589 (96.13%) were functionally annotated. The high-quality near-T2T assemblies provide invaluable resources for molecular breeding and advancing biological and evolutionary research in H. labeo.
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BibTeX
@article{liu2026nearcomplete,
title = {{Near-complete telomere-to-telomere genome assembly of a male barbel steed (Hemibarbus labeo)}},
author = {Wei Liu and Ming Qi and Wenrui Shi and Xiaofeng Zhang and Gaohua Yao and Qinghui Meng and Chen Chen and Tianlun Zheng and Yongyi Jia},
journal = {Scientific Data},
year = {2026},
month = jul,
doi = {10.1038/s41597-026-07825-9},
url = {https://doi.org/10.1038/s41597-026-07825-9},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Near-complete telomere-to-telomere genome assembly of a male barbel steed (Hemibarbus labeo)
AU - Wei Liu
AU - Ming Qi
AU - Wenrui Shi
AU - Xiaofeng Zhang
AU - Gaohua Yao
AU - Qinghui Meng
AU - Chen Chen
AU - Tianlun Zheng
AU - Yongyi Jia
PY - 2026
DA - 2026/07/06
JO - Scientific Data
DO - 10.1038/s41597-026-07825-9
UR - https://doi.org/10.1038/s41597-026-07825-9
AB - The barbel steed (Hemibarbus labeo), an economically important freshwater fish in China, belongs to the order Cypriniformes and the family Cyprinidae. At present, research has been conducted on the basic biology, artificial breeding, aquaculture, and nutritional requirements of H. labeo. However, genome assembly and exploration of the unique genomic composition of the barbel steed are still in their infancy. Previously available genome assemblies were fragmented and incomplete, hindering advances in genomic research and breeding applications. In this study, we generated a near complete telomere-to-telomere (T2T) genome assemblies for a male H. labeo using PacBio HiFi, ONT ultra-long, and Hi-C data. The resulting assemblies span 1,040.46 Mb with contig N50 of 41.15 Mb, and 25 chromosomes were assembled. The quality value (QV) scores were 60.02, and Benchmarking Universal Single-Copy Orthologs (BUSCO) completeness scores were 98.3%. The genome contains a total of 37,023 coding genes, of which 35,589 (96.13%) were functionally annotated. The high-quality near-T2T assemblies provide invaluable resources for molecular breeding and advancing biological and evolutionary research in H. labeo.
SN - 2052-4463
ER -