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Peer-reviewedCC BY 4.0PLOS One

Trends in MD-PhD representation and match outcomes across competitive specialties, 2007–2024

4 affiliations
  1. 1Department of Dermatology, UConn Health, Farmington, Connecticut, United States of America
  2. 2School of Medicine, New York Medical College, Valhalla, New York, United States of America
  3. 3School of Medicine, University of Connecticut, Farmington, Connecticut, United States of America
  4. 4Department of Dermatology, University of California – Los Angeles, Los Angeles, California, United States of America

Abstract

Physician-scientists trained through MD-PhD programs play important roles in translational research. Despite the growing emphasis on research in residency applications, it remains unclear whether competitive specialties demonstrate a preference for MD-PhD graduates. This study evaluates differences in representation and match outcomes between MD-PhD and MD applicants across select specialties from 2007–2024, as well as the influence of specialty-level compensation and structural research infrastructure on outcomes. We analyzed data from the Association of American Medical Colleges (2015–2023), the National MD-PhD Program Outcomes Study (1975–2024), and the National Resident Matching Program’s Charting Outcomes in the Match™ (2014–2024). Chi-square tests compared match rates between MD-PhD and all U.S. MD senior applicants across dermatology, orthopedic surgery, neurosurgery, otolaryngology, plastic surgery, and diagnostic radiology. Negative binomial models measured changes in MD-PhD resident representation. Spearman rank correlations assessed associations between specialty-level physician compensation, NIH departmental funding, number of dedicated Physician-Scientist Training Programs, and MD-PhD outcomes. From 2015–2023, MD-PhD representation among residents remained stable with match rates varying by specialty and year. Dermatology and diagnostic radiology demonstrated strong match outcomes for MD-PhDs, whereas orthopedic surgery showed declining success for MD-PhD applicants. Neurosurgery, otolaryngology, and plastic surgery,had variable or inconsistent trends. Compensation and NIH funding were not significantly correlated with MD-PhD representation or match advantage. Physician-Scientist Training Programs availability showed the strongest associations with both outcomes but was not statistically significant given the small sample size. MD-PhD training does not consistently confer a match advantage in competitive specialties. The availability of research training infrastructure, compensation, and NIH funding may influence MD-PhD match success. Additionally, residency program preferences, such as clinical metrics, as well as MD-PhD applicant preferences may both affect match outcomes. Enhanced mentorship, specialty-specific exposure, and financial support may help support the physician-scientist pipeline across specialties.

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BibTeX
@article{zhou2026trends,
  title = {{Trends in MD-PhD representation and match outcomes across competitive specialties, 2007–2024}},
  author = {Albert E. Zhou and Timothy Klufas and Erik Choi and Yee Won Kim and Jenny J. Kim and Akua Sarfo and Brett Sloan and Hao Feng},
  journal = {PLOS One},
  year = {2026},
  month = sep,
  doi = {10.1371/journal.pone.0357960},
  url = {https://doi.org/10.1371/journal.pone.0357960},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Trends in MD-PhD representation and match outcomes across competitive specialties, 2007–2024
AU  - Albert E. Zhou
AU  - Timothy Klufas
AU  - Erik Choi
AU  - Yee Won Kim
AU  - Jenny J. Kim
AU  - Akua Sarfo
AU  - Brett Sloan
AU  - Hao Feng
PY  - 2026
DA  - 2026/09/10
JO  - PLOS One
DO  - 10.1371/journal.pone.0357960
UR  - https://doi.org/10.1371/journal.pone.0357960
AB  - Physician-scientists trained through MD-PhD programs play important roles in translational research. Despite the growing emphasis on research in residency applications, it remains unclear whether competitive specialties demonstrate a preference for MD-PhD graduates. This study evaluates differences in representation and match outcomes between MD-PhD and MD applicants across select specialties from 2007–2024, as well as the influence of specialty-level compensation and structural research infrastructure on outcomes. We analyzed data from the Association of American Medical Colleges (2015–2023), the National MD-PhD Program Outcomes Study (1975–2024), and the National Resident Matching Program’s Charting Outcomes in the Match™ (2014–2024). Chi-square tests compared match rates between MD-PhD and all U.S. MD senior applicants across dermatology, orthopedic surgery, neurosurgery, otolaryngology, plastic surgery, and diagnostic radiology. Negative binomial models measured changes in MD-PhD resident representation. Spearman rank correlations assessed associations between specialty-level physician compensation, NIH departmental funding, number of dedicated Physician-Scientist Training Programs, and MD-PhD outcomes. From 2015–2023, MD-PhD representation among residents remained stable with match rates varying by specialty and year. Dermatology and diagnostic radiology demonstrated strong match outcomes for MD-PhDs, whereas orthopedic surgery showed declining success for MD-PhD applicants. Neurosurgery, otolaryngology, and plastic surgery,had variable or inconsistent trends. Compensation and NIH funding were not significantly correlated with MD-PhD representation or match advantage. Physician-Scientist Training Programs availability showed the strongest associations with both outcomes but was not statistically significant given the small sample size. MD-PhD training does not consistently confer a match advantage in competitive specialties. The availability of research training infrastructure, compensation, and NIH funding may influence MD-PhD match success. Additionally, residency program preferences, such as clinical metrics, as well as MD-PhD applicant preferences may both affect match outcomes. Enhanced mentorship, specialty-specific exposure, and financial support may help support the physician-scientist pipeline across specialties.
SN  - 1932-6203
ER  -