Peer-reviewedCC BY 4.0Cureus
Non-bacterial Thrombotic Endocarditis Presenting as Cardiogenic Shock With Anterior ST Elevation Revealing an Occult Cholangiocarcinoma: A Case Report
- 1Department of Cardiovascular Intensive Care, Cliniques Universitaires Saint-Luc, Brussels, BEL
- 2Department of Pathology, Cliniques Universitaires Saint-Luc, Brussels, BEL
Abstract
Non-bacterial thrombotic endocarditis (NBTE) associated with cholangiocarcinoma is rare, with only a few case reports described. The diagnosis is usually made after a thrombotic event or stroke. We report the case of a 44-year-old South African woman who presented with cardiogenic shock and ST elevation while receiving rivaroxaban for a recent pulmonary embolism. Autopsy revealed myocardial embolization secondary to NBTE associated with cholangiocarcinoma. This case highlights the value of point-of-care echocardiography in ruling out complications or alternative diagnoses in atypical presentations of acute coronary syndrome. Furthermore, it underscores that, in NBTE, anticoagulation with heparin is the preferred regimen.
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BibTeX
@article{hannesse2026nonbacterial,
title = {{Non-bacterial Thrombotic Endocarditis Presenting as Cardiogenic Shock With Anterior ST Elevation Revealing an Occult Cholangiocarcinoma: A Case Report}},
author = {Colin Hannesse and Francesca Chiara Della Casa and Selda Aydin and Pamela Baldin and Anja Kerschen},
journal = {Cureus},
year = {2026},
month = oct,
doi = {10.7759/cureus.117501},
url = {https://doi.org/10.7759/cureus.117501},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Non-bacterial Thrombotic Endocarditis Presenting as Cardiogenic Shock With Anterior ST Elevation Revealing an Occult Cholangiocarcinoma: A Case Report
AU - Colin Hannesse
AU - Francesca Chiara Della Casa
AU - Selda Aydin
AU - Pamela Baldin
AU - Anja Kerschen
PY - 2026
DA - 2026/10/05
JO - Cureus
DO - 10.7759/cureus.117501
UR - https://doi.org/10.7759/cureus.117501
AB - Non-bacterial thrombotic endocarditis (NBTE) associated with cholangiocarcinoma is rare, with only a few case reports described. The diagnosis is usually made after a thrombotic event or stroke. We report the case of a 44-year-old South African woman who presented with cardiogenic shock and ST elevation while receiving rivaroxaban for a recent pulmonary embolism. Autopsy revealed myocardial embolization secondary to NBTE associated with cholangiocarcinoma. This case highlights the value of point-of-care echocardiography in ruling out complications or alternative diagnoses in atypical presentations of acute coronary syndrome. Furthermore, it underscores that, in NBTE, anticoagulation with heparin is the preferred regimen.
SN - 2168-8184
ER -