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Peer-reviewedCC BY 4.0Neurosurgical Focus: Video

Modern craniopharyngioma management: three illustrative cases with distinct therapeutic strategies

  • A. Yohan Alexander1
  • Crina M. Peterson1
  • Matthew A. Tyler2
  • Emiro Caicedo-Granados2
  • Neal Godse2
  • Kolin Rubel2
  • Daniel J. Guillaume1
  • Garrett Fitzpatrick3
  • Andrew S. Venteicher1
  1. 1Department of Neurosurgery and Center for Skull Base and Pituitary Surgery, University of Minnesota, Minneapolis
  2. 2Department of Otolaryngology–Head and Neck Surgery, University of Minnesota, Minneapolis; and
  3. 3Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota
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Abstract

Craniopharyngioma treatment is increasingly multimodal, with options including surgery, radiation therapy, targeted molecular therapy (for papillary craniopharyngiomas), and a combination of these. As such, management of craniopharyngioma is complex, and strategies depend on patient-specific and tumor-specific factors. Nonetheless, literature regarding treatment selection is lacking. As such, this video details three distinct clinical scenarios of craniopharyngioma management. The authors specifically highlight the role of planned subtotal resection for endocrine preservation in adamantinomatous pediatric craniopharyngioma, gross-total resection for progressive adamantinomatous craniopharyngioma in an adult, and targeted molecular therapy for progressive symptomatic papillary craniopharyngioma.

The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26109

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Cite

BibTeXRIS
BibTeX
@article{alexander2026modern,
  title = {{Modern craniopharyngioma management: three illustrative cases with distinct therapeutic strategies}},
  author = {A. Yohan Alexander and Crina M. Peterson and Matthew A. Tyler and Emiro Caicedo-Granados and Neal Godse and Kolin Rubel and Daniel J. Guillaume and Garrett Fitzpatrick and Andrew S. Venteicher},
  journal = {Neurosurgical Focus: Video},
  year = {2026},
  month = oct,
  doi = {10.3171/2026.7.focvid26109},
  url = {https://doi.org/10.3171/2026.7.focvid26109},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Modern craniopharyngioma management: three illustrative cases with distinct therapeutic strategies
AU  - A. Yohan Alexander
AU  - Crina M. Peterson
AU  - Matthew A. Tyler
AU  - Emiro Caicedo-Granados
AU  - Neal Godse
AU  - Kolin Rubel
AU  - Daniel J. Guillaume
AU  - Garrett Fitzpatrick
AU  - Andrew S. Venteicher
PY  - 2026
DA  - 2026/10/01
JO  - Neurosurgical Focus: Video
DO  - 10.3171/2026.7.focvid26109
UR  - https://doi.org/10.3171/2026.7.focvid26109
AB  - Craniopharyngioma treatment is increasingly multimodal, with options including surgery, radiation therapy, targeted molecular therapy (for papillary craniopharyngiomas), and a combination of these. As such, management of craniopharyngioma is complex, and strategies depend on patient-specific and tumor-specific factors. Nonetheless, literature regarding treatment selection is lacking. As such, this video details three distinct clinical scenarios of craniopharyngioma management. The authors specifically highlight the role of planned subtotal resection for endocrine preservation in adamantinomatous pediatric craniopharyngioma, gross-total resection for progressive adamantinomatous craniopharyngioma in an adult, and targeted molecular therapy for progressive symptomatic papillary craniopharyngioma.  The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26109
SN  - 2643-5217
ER  -