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Peer-reviewedCC BY-NC 4.0The Journal of International Medical Research

Goniotomy as a safe and effective option for glaucoma secondary to typical ocular coloboma: A 12-month follow-up case

  • Yuyan Tang1
  • Yujiao Dan2
  • Zhike Xu2
  • Ziyu Jia2
  • Zhen Li3
  1. 1College of Optometry and Ophthalmology, North Sichuan Medical College, China
  2. 2Department of Ophthalmology, The People’s Hospital of Leshan, China
  3. 3Clinical Medical College & Affiliated Hospital of Chengdu University, China
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Abstract

A woman in her mid-50s presented with lifelong poor vision and progressive, painless bilateral visual deterioration. Clinical evaluation revealed markedly reduced visual acuity, elevated intraocular pressure, bilateral inferior iris coloboma, zonular laxity, nuclear cataracts, partially closed angles and hypoplastic trabecular meshwork. Sequential phacoemulsification with intraocular lens implantation combined with a 120° goniotomy was performed in both eyes. Intraoperatively, residual embryonic tissue overlying the trabecular meshwork and a diminished red reflex were observed. Postoperatively, the patient experienced rapid improvement in visual acuity and intraocular pressure, with restoration of corneal clarity and wide opening of the anterior chamber angles within 1 week. Fundus examination subsequently revealed an inferonasal choroidal coloboma with retinal vessels traversing the defect. At 1-year, visual acuity remained significantly improved and intraocular pressure was stable without medication, with no complications such as hypotony or retinal detachment. This case demonstrates the safety and efficacy of combined cataract extraction and goniotomy in patients with complex anterior segment anomalies associated with iris and choroidal coloboma.

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Cite

BibTeXRIS
BibTeX
@article{tang2026goniotomy,
  title = {{Goniotomy as a safe and effective option for glaucoma secondary to typical ocular coloboma: A 12-month follow-up case}},
  author = {Yuyan Tang and Yujiao Dan and Zhike Xu and Ziyu Jia and Zhen Li},
  journal = {The Journal of International Medical Research},
  year = {2026},
  month = sep,
  doi = {10.1177/03000605261452485},
  url = {https://doi.org/10.1177/03000605261452485},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Goniotomy as a safe and effective option for glaucoma secondary to typical ocular coloboma: A 12-month follow-up case
AU  - Yuyan Tang
AU  - Yujiao Dan
AU  - Zhike Xu
AU  - Ziyu Jia
AU  - Zhen Li
PY  - 2026
DA  - 2026/09/25
JO  - The Journal of International Medical Research
DO  - 10.1177/03000605261452485
UR  - https://doi.org/10.1177/03000605261452485
AB  - A woman in her mid-50s presented with lifelong poor vision and progressive, painless bilateral visual deterioration. Clinical evaluation revealed markedly reduced visual acuity, elevated intraocular pressure, bilateral inferior iris coloboma, zonular laxity, nuclear cataracts, partially closed angles and hypoplastic trabecular meshwork. Sequential phacoemulsification with intraocular lens implantation combined with a 120° goniotomy was performed in both eyes. Intraoperatively, residual embryonic tissue overlying the trabecular meshwork and a diminished red reflex were observed. Postoperatively, the patient experienced rapid improvement in visual acuity and intraocular pressure, with restoration of corneal clarity and wide opening of the anterior chamber angles within 1 week. Fundus examination subsequently revealed an inferonasal choroidal coloboma with retinal vessels traversing the defect. At 1-year, visual acuity remained significantly improved and intraocular pressure was stable without medication, with no complications such as hypotony or retinal detachment. This case demonstrates the safety and efficacy of combined cataract extraction and goniotomy in patients with complex anterior segment anomalies associated with iris and choroidal coloboma.
SN  - 0300-0605
SN  - 1473-2300
ER  -