Regional deprivation and HIV/AIDS outcomes in China: an ecological study using provincial surveillance data

Abstract

Motivations: Regional development in China is uneven, and the annual number of newly reported HIV cases varies across regions. However, empirical studies on the impact of regional development imbalances on HIV/AIDS in China are limited.

Methods: Comparisons were made between regions of different levels of deprivation, examining trends in HIV incidence and AIDS mortality, as well as ratios of HIV incidence and AIDS mortality. Regional deprivation was measured using the General Deprivation Index (GDI). Joinpoint regression was applied to analyze temporal trends, and negative binomial regression was used to estimate incidence and mortality ratios, with the least deprived regions (Q1) as the reference.

Results: Eastern coastal regions had lower GDI values, whereas western regions had higher GDI values, indicating higher deprivation. From 2010 to 2019, the annual percentage change (APC) in HIV incidence in the highest deprivation regions was 10.94% (95% CI: 9.67%–12.22%), and the APC in AIDS mortality was 14.19% (95% CI: 12.32%–16.10%). HIV reported incidence and AIDS mortality ratios in the highest deprivation regions compared to the lowest were 1.30 (95% CI: 1.11–1.52) and 2.19 (95% CI: 1.78–2.70), respectively.

Conclusion: A non-linear association was observed between deprivation and HIV incidence, with Q4 regions bearing the heaviest disease burden, emphasizing the need to prioritize HIV/AIDS prevention and control in these areas.

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BibTeX RIS

BibTeX

@article{xu2026regional,
  title = {{Regional deprivation and HIV/AIDS outcomes in China: an ecological study using provincial surveillance data}},
  author = {Chuanqing Xu and Mengshuang Wang and Lianjiao Dai and Xinyue Chen and Songbai Guo and Xiaoyu Zhao and Yao Wang},
  journal = {BMC Public Health},
  year = {2026},
  month = oct,
  doi = {10.1186/s12889-026-29641-x},
  url = {https://link.springer.com/10.1186/s12889-026-29641-x},
  note = {CC BY 4.0},
}

RIS

TY  - JOUR
TI  - Regional deprivation and HIV/AIDS outcomes in China: an ecological study using provincial surveillance data
AU  - Chuanqing Xu
AU  - Mengshuang Wang
AU  - Lianjiao Dai
AU  - Xinyue Chen
AU  - Songbai Guo
AU  - Xiaoyu Zhao
AU  - Yao Wang
PY  - 2026
DA  - 2026/10/07
JO  - BMC Public Health
DO  - 10.1186/s12889-026-29641-x
UR  - https://link.springer.com/10.1186/s12889-026-29641-x
AB  - Motivations: Regional development in China is uneven, and the annual number of newly reported HIV cases varies across regions. However, empirical studies on the impact of regional development imbalances on HIV/AIDS in China are limited.  Methods: Comparisons were made between regions of different levels of deprivation, examining trends in HIV incidence and AIDS mortality, as well as ratios of HIV incidence and AIDS mortality. Regional deprivation was measured using the General Deprivation Index (GDI). Joinpoint regression was applied to analyze temporal trends, and negative binomial regression was used to estimate incidence and mortality ratios, with the least deprived regions (Q1) as the reference.  Results: Eastern coastal regions had lower GDI values, whereas western regions had higher GDI values, indicating higher deprivation. From 2010 to 2019, the annual percentage change (APC) in HIV incidence in the highest deprivation regions was 10.94% (95% CI: 9.67%–12.22%), and the APC in AIDS mortality was 14.19% (95% CI: 12.32%–16.10%). HIV reported incidence and AIDS mortality ratios in the highest deprivation regions compared to the lowest were 1.30 (95% CI: 1.11–1.52) and 2.19 (95% CI: 1.78–2.70), respectively.  Conclusion: A non-linear association was observed between deprivation and HIV incidence, with Q4 regions bearing the heaviest disease burden, emphasizing the need to prioritize HIV/AIDS prevention and control in these areas.
SN  - 1471-2458
ER  -

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