Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation

Abstract

12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μM) and collagen- (2.0 μg/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H(2)O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H(2)O) were substantial and confirmed by inhibition of platelet surface activation markers.

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BibTeX RIS

BibTeX

@article{falkenberg2026mapuche,
  title = {{Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation}},
  author = {Susan Skanderup Falkenberg and Inge Tarnow and Alfonso Guzman and Per Mølgaard and Henrik Toft Simonsen},
  journal = {Evidence-Based Complementary and Alternative Medicine},
  year = {2026},
  month = oct,
  doi = {10.1155/2012/647620},
  url = {https://hal.science/hal-05773295v1},
  note = {CC BY},
}

RIS

TY  - JOUR
TI  - Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
AU  - Susan Skanderup Falkenberg
AU  - Inge Tarnow
AU  - Alfonso Guzman
AU  - Per Mølgaard
AU  - Henrik Toft Simonsen
PY  - 2026
DA  - 2026/10/01
JO  - Evidence-Based Complementary and Alternative Medicine
DO  - 10.1155/2012/647620
UR  - https://hal.science/hal-05773295v1
AB  - 12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μM) and collagen- (2.0 μg/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H(2)O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H(2)O) were substantial and confirmed by inhibition of platelet surface activation markers.
SN  - 1741-427X
SN  - 1741-4288
ER  -

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