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Peer-reviewedCC BY-NCCaspian journal of internal medicine

Late isolated renal fossa recurrence of clear cell renal cell carcinoma 15 Years post-nephrectomy: A case report and literature review.

4 affiliations
  1. 1Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
  2. 2Department of Urology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
  3. 3Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
  4. 4Department of Surgery, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Abstract

Background

Clear cell renal cell carcinoma is the most common type of renal carcinoma and among them ccRCC is most common. We report a case of a patient diagnosed with renal cell carcinoma (RCC), who exhibited no metastases at the time of nephrectomy but experienced recurrence in the renal fossa after 15 years.Case presentation

We report a late local recurrence of clear cell renal cell carcinoma after 15 year post radical nephrectomy. Lesion find in annual follow-up and initial biopsy show normal hepatic parenchyma we repeat biopsy and confirm local recurrence.Conclusion

The pathology after surgery confinm ccRCC and refer to oncologist for immunotherapy. In this case we emphasize for long term follow-up of RCC.

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BibTeX
@article{shafi2026late,
  title = {{Late isolated renal fossa recurrence of clear cell renal cell carcinoma 15 Years post-nephrectomy: A case report and literature review.}},
  author = {Hamid Shafi and Ali Asghar Rezaei and Hassan Younesi and Ghodsieh Kamrani and Morteza Nasiri and Zahra Shafi},
  journal = {Caspian journal of internal medicine},
  year = {2026},
  month = sep,
  doi = {10.22088/cjim.17.3.678},
  url = {https://europepmc.org/article/MED/42924277},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Late isolated renal fossa recurrence of clear cell renal cell carcinoma 15 Years post-nephrectomy: A case report and literature review.
AU  - Hamid Shafi
AU  - Ali Asghar Rezaei
AU  - Hassan Younesi
AU  - Ghodsieh Kamrani
AU  - Morteza Nasiri
AU  - Zahra Shafi
PY  - 2026
DA  - 2026/09/01
JO  - Caspian journal of internal medicine
DO  - 10.22088/cjim.17.3.678
UR  - https://europepmc.org/article/MED/42924277
AB  - Background  Clear cell renal cell carcinoma is the most common type of renal carcinoma and among them ccRCC is most common. We report a case of a patient diagnosed with renal cell carcinoma (RCC), who exhibited no metastases at the time of nephrectomy but experienced recurrence in the renal fossa after 15 years.Case presentation  We report a late local recurrence of clear cell renal cell carcinoma after 15 year post radical nephrectomy. Lesion find in annual follow-up and initial biopsy show normal hepatic parenchyma we repeat biopsy and confirm local recurrence.Conclusion  The pathology after surgery confinm ccRCC and refer to oncologist for immunotherapy. In this case we emphasize for long term follow-up of RCC.
SN  - 2008-6164
SN  - 2008-6172
ER  -