Corneal diameter distribution and its determinant factors in elderly population: Tehran Geriatric Eye Study
7 affiliations
- 1Department of Epidemiology, Faculty of Health, Ilam University of Medical Sciences, Ilam 69391-77143, Iran
- 2Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran 19839-63113, Iran
- 3Department of Optometry, Department of Physiotherapy, Erbil Technical & Medical Health College, Erbil Polytechnic University, Erbil, Kurdistan Region 44001, Iraq
- 4Department of Optometry, Mashhad University of Medical Sciences, Mashhad 91735-951, Iran
- 5Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran 19839-63113, Iran
- 6Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 14496-14535, Iran
- 7Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran 19686-53111, Iran
Abstract
AIM: To determine the distribution and normative range of corneal diameter in individuals aged over 60, and its association with demographic variables, certain comorbidities, anthropometric measurements, additional ocular biometric indices, and refractive errors. METHODS: This population-based cross-sectional study involved participants aged over 60 residing in Tehran, selected by a multi-stage cluster random sampling. Following the acquisition of informed consent, comprehensive ophthalmological and optometric evaluations, including slit lamp examination, visual acuity assessment, and refraction, were conducted. Ocular biometric parameters, including corneal diameter, were assessed using the Pentacam AXL. RESULTS: A total of 4596 eyes (2292 right eyes and 2304 left eyes) from 2414 older individuals were examined. The mean age with 95% confidence interval (CI) of the study participants was 66.74y (66.51–66.97y), with 58.68% identifying as female. The corneal diameter in the older population had a normal distribution, with a mean of 11.82 mm (95%CI: 11.80–11.84), and a normal range of 11.02–12.62 mm. According to the results of multiple linear regression, a deeper anterior chamber (b=0.30, P<0.001), a university education level (b=0.08, P=0.001), and hyperopia (b=0.04, P=0.005) exhibited a positive correlation with corneal diameter, whereas female gender (b=-0.05, P<0.001), a thicker cornea (b=-0.01, P<0.001), a higher mean keratometry (b=-0.09, P<0.001), and astigmatism (b=-0.03, P=0.013) demonstrated an inverse correlation with corneal diameter. The corneal power was the most important factor that influencing corneal diameter. Nonetheless, the variables of myopia, axial length, diabetes, blood pressure, body mass index (BMI), economic situation, and age exhibited no significant association with corneal diameter. CONCLUSION: The corneal diameter range measured by Pentacam AXL in the elderly population is greater than certain prior studies and lesser than others. The findings serve as a reference for clinicians assessing corneal diameter in the elderly for clinical application.
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BibTeX
@article{lavaei2026corneal,
title = {{Corneal diameter distribution and its determinant factors in elderly population: Tehran Geriatric Eye Study}},
author = {Niloufar Lavaei and Hassan Hashemi and Morad Amir Ahmad and Abbasali Yekta and Reza Pakzad and Ebadallah Shiri Malekabadi and Alireza Jamali and Mehdi Khabazkhoob},
journal = {International Journal of Ophthalmology},
year = {2026},
month = nov,
doi = {10.18240/ijo.2026.11.15},
url = {https://doi.org/10.18240/ijo.2026.11.15},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Corneal diameter distribution and its determinant factors in elderly population: Tehran Geriatric Eye Study
AU - Niloufar Lavaei
AU - Hassan Hashemi
AU - Morad Amir Ahmad
AU - Abbasali Yekta
AU - Reza Pakzad
AU - Ebadallah Shiri Malekabadi
AU - Alireza Jamali
AU - Mehdi Khabazkhoob
PY - 2026
DA - 2026/11/02
JO - International Journal of Ophthalmology
DO - 10.18240/ijo.2026.11.15
UR - https://doi.org/10.18240/ijo.2026.11.15
AB - AIM: To determine the distribution and normative range of corneal diameter in individuals aged over 60, and its association with demographic variables, certain comorbidities, anthropometric measurements, additional ocular biometric indices, and refractive errors. METHODS: This population-based cross-sectional study involved participants aged over 60 residing in Tehran, selected by a multi-stage cluster random sampling. Following the acquisition of informed consent, comprehensive ophthalmological and optometric evaluations, including slit lamp examination, visual acuity assessment, and refraction, were conducted. Ocular biometric parameters, including corneal diameter, were assessed using the Pentacam AXL. RESULTS: A total of 4596 eyes (2292 right eyes and 2304 left eyes) from 2414 older individuals were examined. The mean age with 95% confidence interval (CI) of the study participants was 66.74y (66.51–66.97y), with 58.68% identifying as female. The corneal diameter in the older population had a normal distribution, with a mean of 11.82 mm (95%CI: 11.80–11.84), and a normal range of 11.02–12.62 mm. According to the results of multiple linear regression, a deeper anterior chamber (b=0.30, P<0.001), a university education level (b=0.08, P=0.001), and hyperopia (b=0.04, P=0.005) exhibited a positive correlation with corneal diameter, whereas female gender (b=-0.05, P<0.001), a thicker cornea (b=-0.01, P<0.001), a higher mean keratometry (b=-0.09, P<0.001), and astigmatism (b=-0.03, P=0.013) demonstrated an inverse correlation with corneal diameter. The corneal power was the most important factor that influencing corneal diameter. Nonetheless, the variables of myopia, axial length, diabetes, blood pressure, body mass index (BMI), economic situation, and age exhibited no significant association with corneal diameter. CONCLUSION: The corneal diameter range measured by Pentacam AXL in the elderly population is greater than certain prior studies and lesser than others. The findings serve as a reference for clinicians assessing corneal diameter in the elderly for clinical application.
SN - 2222-3959
SN - 2227-4898
ER -