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PreprintCC BY-NCmedRxiv

Limits of Trial-Adaptive Neural Language Fusion Across Large Language Models in P300 Brain Computer Interfaces

  1. 1BIDMC

Abstract

ObjectivePublished P300-speller fusion schemes fix prior trust regardless of trial reliability; we tested whether a reliability estimate improves on it.

MethodsWe reanalyzed 3,373 archived P300-speller selections from 47 people with ALS (BigP3BCI). A fair, matched-search-space comparison, tuning both a fixed weight and an adaptive policy out-of-fold, was evaluated across 22 evaluable language-model priors up to 46.7B parameters. Two representative priors, GPT-2 and a classical 5-gram, additionally received detailed naive and mechanistic analyses.

ResultsNo priors 95% CI favored adaptive fusion under the fair comparison, despite unexploited oracle headroom at every scale. Under GPT-2, the naive comparison was significantly worse for adaptive fusion; both anchors converged to a degenerate or near-degenerate fair-comparison solution. For the representative anchors, three further controllers failed to convert that headroom into benefit; the fixed-fused posteriors output probability outperformed the best controller for flagging errors (2.8- to 3.8-fold enrichment).

ConclusionA tuned fixed weight is a difficult-to-beat default across the tested scale range; reliability estimation gave no deployable adaptive advantage.

SignificanceAdaptive weighting should be validated against a fairly tuned baseline across model families and scales; in this dataset, the fused outputs confidence identified high-risk selections better than the tested purpose-built ranker.

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BibTeX
@misc{gorenshtein2026limits,
  title = {{Limits of Trial-Adaptive Neural Language Fusion Across Large Language Models in P300 Brain Computer Interfaces}},
  author = {A. Gorenshtein and M. Omar and E. L. Jia and Y. Adiniaev and O. Daniel and J. Kruskal and M. Ahmed and O. R. Brook and E. Klang and Y. Barash},
  howpublished = {medRxiv},
  year = {2026},
  month = aug,
  doi = {10.64898/2026.08.30.26361777},
  url = {https://www.medrxiv.org/content/10.64898/2026.08.30.26361777v1},
  note = {CC BY-NC},
}
RIS
TY  - UNPB
TI  - Limits of Trial-Adaptive Neural Language Fusion Across Large Language Models in P300 Brain Computer Interfaces
AU  - A. Gorenshtein
AU  - M. Omar
AU  - E. L. Jia
AU  - Y. Adiniaev
AU  - O. Daniel
AU  - J. Kruskal
AU  - M. Ahmed
AU  - O. R. Brook
AU  - E. Klang
AU  - Y. Barash
PY  - 2026
DA  - 2026/08/30
PB  - medRxiv
DO  - 10.64898/2026.08.30.26361777
UR  - https://www.medrxiv.org/content/10.64898/2026.08.30.26361777v1
AB  - ObjectivePublished P300-speller fusion schemes fix prior trust regardless of trial reliability; we tested whether a reliability estimate improves on it.  MethodsWe reanalyzed 3,373 archived P300-speller selections from 47 people with ALS (BigP3BCI). A fair, matched-search-space comparison, tuning both a fixed weight and an adaptive policy out-of-fold, was evaluated across 22 evaluable language-model priors up to 46.7B parameters. Two representative priors, GPT-2 and a classical 5-gram, additionally received detailed naive and mechanistic analyses.  ResultsNo priors 95% CI favored adaptive fusion under the fair comparison, despite unexploited oracle headroom at every scale. Under GPT-2, the naive comparison was significantly worse for adaptive fusion; both anchors converged to a degenerate or near-degenerate fair-comparison solution. For the representative anchors, three further controllers failed to convert that headroom into benefit; the fixed-fused posteriors output probability outperformed the best controller for flagging errors (2.8- to 3.8-fold enrichment).  ConclusionA tuned fixed weight is a difficult-to-beat default across the tested scale range; reliability estimation gave no deployable adaptive advantage.  SignificanceAdaptive weighting should be validated against a fairly tuned baseline across model families and scales; in this dataset, the fused outputs confidence identified high-risk selections better than the tested purpose-built ranker.
ER  -