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Peer-reviewedCC BY-NC-NDJournal of vascular surgery cases and innovative techniques

Methylene blue-guided parenchyma-sparing ex vivo resection and autotransplantation for a type III renal arteriovenous fistula with large renal vein aneurysm: A technical case report.

  1. 1Unit of Vascular Surgery, Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli I.R.C.C.S., Rome, Italy.
  2. 2Unit of Vascular Surgery, Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli I.R.C.C.S. - Università Cattolica del Sacro Cuore, Rome, Italy.

Abstract

High-flow renal arteriovenous malformations (AVMs), type III with vein aneurysms, are rare and often require nephrectomy. A 54-year-old man presented with lumbar pain and hematuria. Computed tomography angiography revealed an 8- × 12-cm right renal vein aneurysm and a type III arteriovenous fistula occupying >30% of the kidney. After ex vivo nephrectomy with cold perfusion, selective methylene blue injection delineated the AVM nidus and parenchyma, guiding resection and excision. The procedure was performed by a multidisciplinary team including a vascular surgeon, transplant surgeon, and urologist. The kidney was reconstructed and reimplanted. Postoperative creatinine levels stabilized at 1.10 mg/dL, and computed tomography angiography confirmed AVM exclusion and preserved perfusion. Methylene blue mapping can enable parenchyma-sparing repair in selected cases.

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BibTeX
@article{borghese2026methylene,
  title = {{Methylene blue-guided parenchyma-sparing ex vivo resection and autotransplantation for a type III renal arteriovenous fistula with large renal vein aneurysm: A technical case report.}},
  author = {Ottavia Borghese and Francesco Sposato and Yamume Tshomba},
  journal = {Journal of vascular surgery cases and innovative techniques},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jvscit.2026.102511},
  url = {https://europepmc.org/article/MED/42898592},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Methylene blue-guided parenchyma-sparing ex vivo resection and autotransplantation for a type III renal arteriovenous fistula with large renal vein aneurysm: A technical case report.
AU  - Ottavia Borghese
AU  - Francesco Sposato
AU  - Yamume Tshomba
PY  - 2026
DA  - 2026/09/16
JO  - Journal of vascular surgery cases and innovative techniques
DO  - 10.1016/j.jvscit.2026.102511
UR  - https://europepmc.org/article/MED/42898592
AB  - High-flow renal arteriovenous malformations (AVMs), type III with vein aneurysms, are rare and often require nephrectomy. A 54-year-old man presented with lumbar pain and hematuria. Computed tomography angiography revealed an 8- × 12-cm right renal vein aneurysm and a type III arteriovenous fistula occupying >30% of the kidney. After ex vivo nephrectomy with cold perfusion, selective methylene blue injection delineated the AVM nidus and parenchyma, guiding resection and excision. The procedure was performed by a multidisciplinary team including a vascular surgeon, transplant surgeon, and urologist. The kidney was reconstructed and reimplanted. Postoperative creatinine levels stabilized at 1.10 mg/dL, and computed tomography angiography confirmed AVM exclusion and preserved perfusion. Methylene blue mapping can enable parenchyma-sparing repair in selected cases.
SN  - 2468-4287
ER  -