Numerical speckle reduction for optical coherence tomography based on an analytical image formation model

Abstract

Speckle is an intrinsic granular pattern that limits the effective resolution of optical coherence tomography (OCT). We propose a numerical speckle reduction method using the "real part of a shifted complex conjugate product" (real-SCCP), which is a new image representation designed based on an analytical imaging model of OCT. In the real-SCCP image representation, the speckle can be fully numerically modulated after OCT signal acquisition. By averaging multiple SCCP images with different speckle realizations, the speckle is effectively reduced. Furthermore, this method enables clear visualization of structures in tumor spheroids and zebrafish eyes, and significantly outperforms conventional frame-averaging-based speckle reduction techniques.

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BibTeX RIS

BibTeX

@misc{wang2026numerical,
  title = {{Numerical speckle reduction for optical coherence tomography based on an analytical image formation model}},
  author = {Xibo Wang and Shuichi Makita and Nobuhisa Tateno and Suzuyo Komeda and Cunyou Bao and Atsuko Furukawa and Satoshi Matsusaka and Makoto Kobayashi and Yoshiaki Yasuno},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2605.13443},
  eprint = {2605.13443},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2605.13443},
  note = {CC BY-SA 4.0},
}

RIS

TY  - UNPB
TI  - Numerical speckle reduction for optical coherence tomography based on an analytical image formation model
AU  - Xibo Wang
AU  - Shuichi Makita
AU  - Nobuhisa Tateno
AU  - Suzuyo Komeda
AU  - Cunyou Bao
AU  - Atsuko Furukawa
AU  - Satoshi Matsusaka
AU  - Makoto Kobayashi
AU  - Yoshiaki Yasuno
PY  - 2026
DA  - 2026/09/01
PB  - arXiv
DO  - 10.48550/arxiv.2605.13443
UR  - https://arxiv.org/abs/2605.13443
AB  - Speckle is an intrinsic granular pattern that limits the effective resolution of optical coherence tomography (OCT). We propose a numerical speckle reduction method using the "real part of a shifted complex conjugate product" (real-SCCP), which is a new image representation designed based on an analytical imaging model of OCT. In the real-SCCP image representation, the speckle can be fully numerically modulated after OCT signal acquisition. By averaging multiple SCCP images with different speckle realizations, the speckle is effectively reduced. Furthermore, this method enables clear visualization of structures in tumor spheroids and zebrafish eyes, and significantly outperforms conventional frame-averaging-based speckle reduction techniques.
ER  -

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