Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer
535 BC3195, a novel cadherin-3 targeting antibody drug conjugate, combined with pembrolizumab in patients with advanced solid malignancies: preliminary results from a phase I/II study (BC3195-103/G36)
5 affiliations
- 11 Guangdong Lung Cancer Institute, Guangdong Provincial People`s Hospital, Guangzhou, Guangdong, China
- 2Center for Environment and Population Health, Griffith University, Nathan, Queensland, Australia
- 3Guangdong Provincial People’s Hospital, Guangzhou, Guangdong, China
- 4Guangdong Lung Cancer Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China
- 5Biocity Biopharmaceutics Co. Ltd, Shanghai, China
Related
- Domain-resolved epitope mapping of B7-H3-targeting VHH-Fcs defines isoform-selective binders for antibody-drug conjugate development
- Targeting CD28 on T lineage malignancies with chimeric antigen receptor T cells
- Targeting tumor-selective membrane-associated PCNA enables selective antibody-drug conjugate therapy.
- Quantitative Systems Pharmacology Model for Trop-2 Targeting Antibody-Drug Conjugate in Triple-Negative Breast Cancer
- Antibody-drug conjugate combination therapy targeting LGR5 and MET with different payloads enhances efficacy in preclinical colorectal cancer models
BibTeX
@article{wu2026bc3195,
title = {{535 BC3195, a novel cadherin-3 targeting antibody drug conjugate, combined with pembrolizumab in patients with advanced solid malignancies: preliminary results from a phase I/II study (BC3195-103/G36)}},
author = {Yi-Long Wu and Hai-jun Guo and Chongrui Xu and Fa-Man Xiao and Ji-Lin Guan and Yue-Li Sun and Xiang-Yun Ye and Yi-Wei Wang},
journal = {Journal for ImmunoTherapy of Cancer},
year = {2026},
month = nov,
doi = {10.1136/jitc-2026-sitc2026.0535},
url = {https://doi.org/10.1136/jitc-2026-sitc2026.0535},
note = {CC BY},
}
RIS
TY - JOUR
TI - 535 BC3195, a novel cadherin-3 targeting antibody drug conjugate, combined with pembrolizumab in patients with advanced solid malignancies: preliminary results from a phase I/II study (BC3195-103/G36)
AU - Yi-Long Wu
AU - Hai-jun Guo
AU - Chongrui Xu
AU - Fa-Man Xiao
AU - Ji-Lin Guan
AU - Yue-Li Sun
AU - Xiang-Yun Ye
AU - Yi-Wei Wang
PY - 2026
DA - 2026/11/06
JO - Journal for ImmunoTherapy of Cancer
DO - 10.1136/jitc-2026-sitc2026.0535
UR - https://doi.org/10.1136/jitc-2026-sitc2026.0535
SN - 2051-1426
ER -