The development and psychometric evaluation of the Post Activity Symptom Scale (PASS) for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome.
- 1University of Manchester.ac.uk
Abstract
Purpose: To develop and psychometrically evaluate a new scale measuring post-exertional malaise in people with myalgic encephalomyelitis (ME)/ chronic fatigue syndrome (CFS). Methods: A draft scale was co-produced with patient and clinician advisory groups. After extensive pilot testing, adults with ME/CFS completed the Post Activity Symptom Scale online and repeated it two weeks later to assess test-retest reliability and sensitivity to change. Rasch analysis assessed each domain for unidimensionality, targeting, internal reliability, item fit and local dependency. Then Rasch-transformed interval data and parametric statistics were used to assess criterion-related and discriminant validity (by comparison with measures of physical health and ME/CFS severity), test-retest reliability and minimal detectable difference. Results: The item regarding delay in PEM onset was an under-discriminating misfit anomaly which was inconsistent with the remaining PASS items. When this was removed, the PASS was a unidimensional, psychometrically robust scale. Criterion-related validity (r=0.58, p<0.001) was moderate and highly significant, discriminant validity (p<0.001) and test-retest reliability (ICC = 0.81) were excellent. The minimal detectable difference was 1.93/100. Participants found the PASS easy to complete, comprehensive and relevant. Conclusion: The Post Activity Symptom Scale is a valid, reliable, sensitive measure of people of PEM in ME/CFS
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BibTeX
@misc{horton2026development,
title = {{The development and psychometric evaluation of the Post Activity Symptom Scale (PASS) for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome.}},
author = {M. Horton and S. F. Tyson and R. Fleming},
howpublished = {medRxiv},
year = {2026},
month = nov,
doi = {10.64898/2026.11.06.26367424},
url = {https://www.medrxiv.org/content/10.64898/2026.11.06.26367424v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - The development and psychometric evaluation of the Post Activity Symptom Scale (PASS) for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome.
AU - M. Horton
AU - S. F. Tyson
AU - R. Fleming
PY - 2026
DA - 2026/11/06
PB - medRxiv
DO - 10.64898/2026.11.06.26367424
UR - https://www.medrxiv.org/content/10.64898/2026.11.06.26367424v1
AB - Purpose: To develop and psychometrically evaluate a new scale measuring post-exertional malaise in people with myalgic encephalomyelitis (ME)/ chronic fatigue syndrome (CFS). Methods: A draft scale was co-produced with patient and clinician advisory groups. After extensive pilot testing, adults with ME/CFS completed the Post Activity Symptom Scale online and repeated it two weeks later to assess test-retest reliability and sensitivity to change. Rasch analysis assessed each domain for unidimensionality, targeting, internal reliability, item fit and local dependency. Then Rasch-transformed interval data and parametric statistics were used to assess criterion-related and discriminant validity (by comparison with measures of physical health and ME/CFS severity), test-retest reliability and minimal detectable difference. Results: The item regarding delay in PEM onset was an under-discriminating misfit anomaly which was inconsistent with the remaining PASS items. When this was removed, the PASS was a unidimensional, psychometrically robust scale. Criterion-related validity (r=0.58, p<0.001) was moderate and highly significant, discriminant validity (p<0.001) and test-retest reliability (ICC = 0.81) were excellent. The minimal detectable difference was 1.93/100. Participants found the PASS easy to complete, comprehensive and relevant. Conclusion: The Post Activity Symptom Scale is a valid, reliable, sensitive measure of people of PEM in ME/CFS
ER -