Secondary Pulmonary Alveolar Proteinosis after Allogeneic Hematopoietic Stem Cell Transplantation in the…

Abstract

Secondary pulmonary alveolar proteinosis (SPAP) is rare and often results in poor outcomes; therefore, it is crucial to diagnose and treat it appropriately. A 23-year-old man who received allogeneic hematopoietic stem cell transplantation (allo-HSCT) 18 months before presentation was diagnosed with SPAP after allo-HSCT in the setting of an RSV infection. The patient's respiratory symptoms improved after treatment for RSV infection, and SPAP gradually improved during the follow-up period. This case suggests that SPAP should be considered in post-HSCT patients with persistent respiratory symptoms or radiological abnormalities in the setting of an RSV infection.

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BibTeX RIS

BibTeX

@article{mori2026secondary,
  title = {{Secondary Pulmonary Alveolar Proteinosis after Allogeneic Hematopoietic Stem Cell Transplantation in the Setting of an Respiratory Syncytial Virus Infection: A Case Report}},
  author = {Yuki Mori and Koichi Nakase and Risa Hashida and Yuichiro Nawa and Norihiko Nakanishi},
  journal = {Internal Medicine},
  year = {2026},
  month = oct,
  doi = {10.2169/internalmedicine.5740-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_5740-25/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Secondary Pulmonary Alveolar Proteinosis after Allogeneic Hematopoietic Stem Cell Transplantation in the Setting of an Respiratory Syncytial Virus Infection: A Case Report
AU  - Yuki Mori
AU  - Koichi Nakase
AU  - Risa Hashida
AU  - Yuichiro Nawa
AU  - Norihiko Nakanishi
PY  - 2026
DA  - 2026/10/22
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.5740-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_5740-25/_article
AB  - Secondary pulmonary alveolar proteinosis (SPAP) is rare and often results in poor outcomes; therefore, it is crucial to diagnose and treat it appropriately. A 23-year-old man who received allogeneic hematopoietic stem cell transplantation (allo-HSCT) 18 months before presentation was diagnosed with SPAP after allo-HSCT in the setting of an RSV infection. The patient's respiratory symptoms improved after treatment for RSV infection, and SPAP gradually improved during the follow-up period. This case suggests that SPAP should be considered in post-HSCT patients with persistent respiratory symptoms or radiological abnormalities in the setting of an RSV infection.
SN  - 1349-7235
SN  - 0918-2918
ER  -

Abstract

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