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Peer-reviewedCC BY 4.0Molecules

Formation and Characterization of Nanoparticles from Avocado Peel Extract and Bovine Serum Albumin

  • Lino Sánchez-Segura1
  • Laura Elizabeth Zavala-García1
  • Juan Vázquez-Martínez2
  • Emir Martínez-Gutiérrez3
  1. 1Departamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional-Unidad Irapuato, Km 9.6 Libramiento Norte Carretera Irapuato-León, Irapuato 36824, Guanajuato, Mexico
  2. 2Departamento de Ingeniería Química, Tecnológico Nacional de México/ITS Irapuato, Carretera Irapuato-Silao Km 12.5, Irapuato 36821, Guanajuato, Mexico
  3. 3Secretaría de Ciencia, Humanidades, Tecnología e Innovación (SECIHTI)-Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional-Unidad Irapuato, Km 9.6 Libramiento Norte Carretera Irapuato-León, Irapuato 36824, Guanajuato, Mexico
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Abstract

Avocado peel is a source of polyphenols, which are generally light-sensitive and have low long-term stability. Nanoencapsulation could overcome this limitation. The aim of this work was to formulate bovine serum albumin (BSA) nanoparticles containing avocado peel extract and to determine the effect of increased extract concentration on their characteristics. We characterized the nanoparticles using transmission electron microscopy (TEM), ζ-potential and Fourier transform infrared (FTIR) spectroscopy. The results showed that nanoparticle yield decreased by 17.1% when 2.5 mg of extract was added compared with empty nanoparticles. The smallest nanoparticles, obtained with 2.5 mg of extract, had an effective diameter of 258.7 nm and a circular shape. As the amount of extract increased, the nanoparticle shapes shifted from elliptical to irregular, suggesting that the extract and its concentration affected the nanostructure. The FTIR spectra showed perturbations induced by the interaction between the extract and albumin. Significant FTIR peaks were observed at 3290 cm−1 and 1644 cm−1, suggesting that the extract was successfully encapsulated within the BSA matrix.

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Cite

BibTeXRIS
BibTeX
@article{sanchezsegura2026formation,
  title = {{Formation and Characterization of Nanoparticles from Avocado Peel Extract and Bovine Serum Albumin}},
  author = {Lino Sánchez-Segura and Laura Elizabeth Zavala-García and Juan Vázquez-Martínez and Emir Martínez-Gutiérrez},
  journal = {Molecules},
  year = {2026},
  month = oct,
  doi = {10.3390/molecules31203649},
  url = {https://www.mdpi.com/1420-3049/31/20/3649},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Formation and Characterization of Nanoparticles from Avocado Peel Extract and Bovine Serum Albumin
AU  - Lino Sánchez-Segura
AU  - Laura Elizabeth Zavala-García
AU  - Juan Vázquez-Martínez
AU  - Emir Martínez-Gutiérrez
PY  - 2026
DA  - 2026/10/01
JO  - Molecules
DO  - 10.3390/molecules31203649
UR  - https://www.mdpi.com/1420-3049/31/20/3649
AB  - Avocado peel is a source of polyphenols, which are generally light-sensitive and have low long-term stability. Nanoencapsulation could overcome this limitation. The aim of this work was to formulate bovine serum albumin (BSA) nanoparticles containing avocado peel extract and to determine the effect of increased extract concentration on their characteristics. We characterized the nanoparticles using transmission electron microscopy (TEM), ζ-potential and Fourier transform infrared (FTIR) spectroscopy. The results showed that nanoparticle yield decreased by 17.1% when 2.5 mg of extract was added compared with empty nanoparticles. The smallest nanoparticles, obtained with 2.5 mg of extract, had an effective diameter of 258.7 nm and a circular shape. As the amount of extract increased, the nanoparticle shapes shifted from elliptical to irregular, suggesting that the extract and its concentration affected the nanostructure. The FTIR spectra showed perturbations induced by the interaction between the extract and albumin. Significant FTIR peaks were observed at 3290 cm−1 and 1644 cm−1, suggesting that the extract was successfully encapsulated within the BSA matrix.
SN  - 1420-3049
ER  -