Mechanical and Gravimetric Response of Surgical Suture Biomaterials to Commercial Mouthrinses During Static In Vitro Exposure.
- 1Institute of Biomedical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technology, Wiejska 45C, 15-351 Bialystok, Poland.
- 2Digital Dentistry Lab, Department of Dental and Maxillofacial Radiodiagnostics, Faculty of Medical Dentistry, Medical University of Lublin, 20-059 Lublin, Poland.
- 3Department of Computerization and Robotics of Production, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland.
Abstract
Surgical sutures are temporary load-bearing biomaterials whose performance in the oral cavity may be altered by postoperative mouthrinses. Seven USP 4-0 suture materials were immersed in four commercial mouthrinses for 3, 7, 10, and 14 days in a balanced factorial design (n = 3 per condition), with artificial saliva as a time-matched reference. Maximum breaking force (Fmax), apparent wet-state mass change, and solution pH were evaluated, and Day 14 re-dried mass was determined in an additional cohort (n = 5). Fmax was significantly affected by material, mouthrinse, time, and all interaction terms (p < 0.001), with material showing the largest main effect (partial η² = 0.957). Mean Fmax decreased by 57.1% for PGA and 53.3% for PGLA between Days 3 and 14 when averaged across mouthrinses. PGLA also declined in artificial saliva (-49.1%), showing that temporal loss was not exclusive to mouthrinse exposure. Mean apparent wet-state mass change ranged from 85.1% for silk to 8.5% for nylon 66 and showed a weak pooled association with Fmax (r = -0.163, p = 0.086); suture-related pH shifts were small. Under static immersion, response was specific to the material-formulation pair and evolved with time. Continuous immersion without medium renewal or prior salivary conditioning does not reproduce intermittent clinical mouthrinse use.
Related
- Prospective multicentric validation of a novel uroflowmetry device (Pflow™) against conventional gravimetric uroflowmetry.
- Structure-based mechanical properties of human carotid arteries and their effect on stress-strain response
- Advancing regenerative biomaterials and translational strategies in orthopaedic traumatology.
- Comparative Assessment of Fungal Biofilm Development on PEEK and PDMS Biomaterials and the Antifungal Potential of TiO₂/ZrO₂-Coated PEEK.
- Hyaluronic Acid-Based Biomaterials in Tissue Engineering: From Molecular Properties to Re-Generative Applications
BibTeX
@article{choszczyk2026mechanical,
title = {{Mechanical and Gravimetric Response of Surgical Suture Biomaterials to Commercial Mouthrinses During Static In Vitro Exposure.}},
author = {Alicja Choszczyk and Anna Ciołko and Wiktoria Nowak and Leszek Szalewski and Ewelina Kosicka and Żaneta Anna Mierzejewska},
journal = {Bioengineering (Basel, Switzerland)},
year = {2026},
month = oct,
doi = {10.3390/bioengineering13101178},
url = {https://europepmc.org/article/MED/42939033},
note = {CC BY},
}
RIS
TY - JOUR
TI - Mechanical and Gravimetric Response of Surgical Suture Biomaterials to Commercial Mouthrinses During Static In Vitro Exposure.
AU - Alicja Choszczyk
AU - Anna Ciołko
AU - Wiktoria Nowak
AU - Leszek Szalewski
AU - Ewelina Kosicka
AU - Żaneta Anna Mierzejewska
PY - 2026
DA - 2026/10/09
JO - Bioengineering (Basel, Switzerland)
DO - 10.3390/bioengineering13101178
UR - https://europepmc.org/article/MED/42939033
AB - Surgical sutures are temporary load-bearing biomaterials whose performance in the oral cavity may be altered by postoperative mouthrinses. Seven USP 4-0 suture materials were immersed in four commercial mouthrinses for 3, 7, 10, and 14 days in a balanced factorial design (n = 3 per condition), with artificial saliva as a time-matched reference. Maximum breaking force (Fmax), apparent wet-state mass change, and solution pH were evaluated, and Day 14 re-dried mass was determined in an additional cohort (n = 5). Fmax was significantly affected by material, mouthrinse, time, and all interaction terms (p < 0.001), with material showing the largest main effect (partial η² = 0.957). Mean Fmax decreased by 57.1% for PGA and 53.3% for PGLA between Days 3 and 14 when averaged across mouthrinses. PGLA also declined in artificial saliva (-49.1%), showing that temporal loss was not exclusive to mouthrinse exposure. Mean apparent wet-state mass change ranged from 85.1% for silk to 8.5% for nylon 66 and showed a weak pooled association with Fmax (r = -0.163, p = 0.086); suture-related pH shifts were small. Under static immersion, response was specific to the material-formulation pair and evolved with time. Continuous immersion without medium renewal or prior salivary conditioning does not reproduce intermittent clinical mouthrinse use.
SN - 2306-5354
ER -