Molecular biology & gene regulation
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- Interpretable AI-guided discovery of degradable ionizable lipids with enhanced hepatic mRNA delivery in vivo
- Structures and molecular mechanisms of RAD54B in modulating homologous recombination
- KMT2B facilitates long-range gene regulation through LINE1 elements
- Whole blood transcriptomics atlas across human diseases
- Bridging communication gaps across the biomedical ecosystem
- Human cytomegalovirus antagonizes SMC5/6 driven genome silencing via UL35 instituted proteasomal degradation of SLF2
- Development of loop-mediated isothermal amplification (LAMP) combined with a lateral flow dipstick DNA biosensor for detection of α thalassemia 1 [Southeast Asia (SEA), --SEA deletion]
- An NKX2-3/5/6 homolog is required downstream of BMP signaling to pattern the sensory-adhesive organ of a tunicate larva
- GTPase GBP7 promotes HSV-1 infection by interacting with and activating eEF1A1 to accelerate the protein translation process
- Omicron SARS-CoV-2 shows NRP1-linked susceptibility in adipose-derived MSCs and alters primitive cord blood CD34⁺ HSPCs
- Transcriptional programs controlling sporulation in Phytophthora respond to nutrition, humidity, and cryptochrome-mediated light signals
- Sequence‐encoded dynamics diversify allostery within a conserved protein scaffold
- Valorization of icariin via α-l-rhamnosidase mutant immobilized on UiO-66-NH2: an efficient and recyclable biocatalytic system for icariside I production
- A literature-weighted composite index for integrating reproductive dysfunction and cancer-associated molecular features: a reproducible computational pipeline
- Loss of nono impairs cardiac morphogenesis and excitation–contraction coupling via the PI3K/Akt pathway in zebrafish
- Stromal-derived Anxa1 engages neutrophil Fpr2 to brake the Nlrp3 inflammasome in otitis media with effusion
- Bioassay-guided isolation and characterization of antiplasmodial compounds from Ximenia caffra bark and their interaction with PfHsp70-1
- Whole blood metabolomics reveals coordinated redox-one-carbon axis disruption in NSCLC: a pilot study in an Indian cohort
- Split-intein-mediated engineering of VSV-G-free extracellular vesicles for enhanced cargo loading and delivery of functional proteins
- Shared household environment structures the gut microbiota in a large family cohort with central areolar choroidal dystrophy
- Site-selective Halogenation of Aromatic C-H Bonds via Electrocatalytic Flavin Adenine Dinucleotide Cofactor Regeneration
- Mechanistic basis of μ-opioid receptor allosteric modulation from molecular simulations
- Conformational Heterogeneity and Local Electronic Structure in Wild-Type and Arctic Amyloid-Β42
- Customizable Approach to Conformer Space Discretization using Torsion Angular Bin Strings (customTABS)
- Solid-phase synthesis and structure-degradation relationships of VHL-recruiting PROTACs for preferential histone deacetylase 6 degradation