Structural biology
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154 studies
- Eps2Fold: a rapid method to characterize G-quadruplex DNA structures using single absorbance spectra
- Fragment-based drug discovery strategy reveals an unprecedented allosteric binding site in Mycobacterium tuberculosis DNA gyrase
- DNA Geometry Around Highly Transcribed Bacterial Genes
- In-column Synthesis and Atomic-resolution Electron Microscopic Analysis of Metastable Reactive Nitrides
- Control of ice thickness in cryo-EM via confinement
- Quinone Reductase 2 Dimerization is Dynamically Driven by Ligand Binding
- Structural evolution of LEAFY reveals DNA-mediated cooperativity and dimerization shifts at the water-to-land transition
- Single photon emitters in hBN: Limitations of atomic resolution imaging and potential sources of error
- Cryo-EM structure of bixafen-bound S. cerevisiae complex II unravels SDHI specificity against pathogenic fungi
- Room Temperature Structures of Solvated Organic Molecules Enabled by Liquid Cell Electron Diffraction
- The role of absorption in 3D electron diffraction dynamical structure refinement
- Carbon nanotubes as the supporting film for cryo-EM specimen preparation.
- Nanoscale stacking disorder and Jahn-Teller distortion in Brochantite, Cu4SO4(OH)6, revealed by 3D electron diffraction
- Signal peptidase complexes set species-specific rules for signal peptide cleavage
- Programmable gold nanoparticle conjugates enable precise AMPA receptor localization at brain synapses by cryo-ET
- Probing the interaction between the WDR41 7CD loop of the C9ORF72 complex and purified PQLC2
- VDAC2 stabilizes a membrane-inserted, primed intermediate of BAX activation
- A multiscale study to characterize SHAPE probe/ RNA molecules pre-reactive complex and its role in initiating the SHAPE reaction
- A DltE–DltD–DltX interaction network regulates lipoteichoic acid D-alanylation and Lactiplantibacillus plantarum-mediated growth promotion in Drosophila
- Antibody CDR-H3 loop flexibility: Insights from X-ray crystallography, structural bioinformatics, and the limits of current deep learning methods
- Plasmodium falciparum Myosin B is a slow motor optimized for force generation
- Structural comparison of homologous protein-RNA interfaces reveals widespread overall conservation contrasted with versatility in polar contacts
- Conformational landscapes in cryo-electron tomography data based on molecular dynamics simulations
- Rapid Fabrication of Sub‐100 µm Microstructures In Situ via Femtosecond Laser for Correlative Imaging of Rare Cells
- MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography