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Bioinformatics & computational biology

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2,099 studies

  1. OFC-SV: Interpreting structural variants in African and Asian cohorts with non-syndromic orofacial clefts
    K. Chen, Y. Chung, T. Becker +2
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  2. LongVerse: verified AI agents for Nanopore and PacBio DNA methylation analysis
    Yang Liu, Qiuyang Zhang, Sheng Li
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxivPMC
  3. CROSS-PLATFORM CONCORDANCE ANALYSIS REVEALS ROBUST AND CLINICALLY RELEVANT GENE SIGNATURES IN BREAST CANCER
    J. O. Imhanbor, A. Fatai
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  4. MIEN: a deep-learning model for pocket-conditioned glycan pose and conformation discrimination
    X. Huang, Z. Tian
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  5. Metabolite-centric Knowledge Graph Unveils Predictive and Mechanistic Insights through Self-supervised Multimodal Learning
    Y. Lu, X. Guan, W. Wu +4
    bioRxivPreprintAll rights reservedFull textBioinformatics & computational biologybioRxiv
  6. scOmnom: scalable end-to-end single-cell RNA-seq analysis with auditable resolution selection
    I. M. Hu, A. Kovynev, A. S. Meijnikman +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  7. mixKIN: An ancestry-aware kinship estimation method for low coverage genomes
    M. S. Kılıc, A.-S. Malaspinas, D. Koptekin
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  8. ClonoDeconv: reference-based α - β paired recurrent clonotype proportion estimation from bulk-TCR sequencing
    Y. Zhou, E. Antoun, M. Pereira Pinho +7
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  9. Trust, but Verify: Epistemic Uncertainty-Gated Pseudo-Labeling for Safer Semi-Supervised Malaria Screening
    A. Kumar, A. Anand, L. Chhetri
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  10. DCAF: Unifying Data Validity, Evaluation Validity and Predictive Modeling for Single-cell Perturbation Simulation
    T. Xia, C. Lei, N. Chen +8
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  11. Metalink: Joint taxonomic and functional profiling of metagenomes and metatranscriptomes across resolution scales
    L. Li, Y. Wang
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  12. DeepD enables efficient genome modeling and controllable long-context sequence generation across domains of life
    J. Lai, B. Xin, Z. Wang +14
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  13. Order Matters: Ambient RNA correction confounds doublet detection in single-cell RNA sequencing
    M. Meier, G. Howitt, C. V. Grima +9
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  14. Warmth shifts rather than speeds transcriptomic ageing in the malaria mosquito Anopheles gambiae
    K. Sinha, N. Ghosh, S. Banerjee
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  15. SpectroBird: Event-Level Vocalization Detection and Curation for Avian Ecology
    E. G. Dreyer, P. Gokhale, V. Chandran +9
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  16. Hidden introns and repeated gains shape the heavily interrupted tRNA genes of Asgard archaea
    S. Goswami, A. K. Ghosh, K. Sinha
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  17. Biological and technical spatial variation in spatial transcriptomics
    K. C. Jackson, G. Gorin, L. Pachter
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  18. Why 627 BindCraft2 trajectories produced zero binders
    W. Fu, J. Chen, X. Wu
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  19. BCell-Epitope-Prediction: A local, reproducible pipeline for multi-epitope vaccine design: integration and structural validation against a panel of PDB antigen-antibody complexes
    E. L. E. Sierra Vera, B. Pueche Granados, C. E. Gomez +1
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  20. Hubness and local scaling in paired T cell receptor distance spaces
    K. Maire, W. Zheng
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  21. Representation-aware conformal prediction for reliable uncertainty quantification in drug-target affinity
    Xinya Li, Yaxin Zhang, Ximin Zeng +3
    BioinformaticsPeer-reviewedCC BY 4.0Full textBioinformatics & computational biologyCrossrefPMC
  22. Data-Driven Virus Discovery with Virushunter and Virusgatherer
    NAR genomics and bioinformaticsPeer-reviewedCC BYFull textBioinformatics & computational biologyEurope PMC
  23. Physiology-Informed Sparse Identification of Dynamic Crop Models
    Corné Verburg, Alexander Heinlein, Fred van Eeuwijk +1
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyEvolutionary biologyarXiv
  24. Probability generating functions for epidemiological time series
    Mariah C. Boudreau, Guillaume St-Onge
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyEvolutionary biologyarXiv
  25. AutoNovo: Agentic Program Search Discovers Transferable Nucleic Acid Design Algorithms
    Joel Shor, Subhashini Venugopalan
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv