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Clinical trials & evidence synthesis

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165 studies

  1. Mapping the literature employed to teach law in universities in Anglophonic and Hispanophone countries in the nineteenth century to explore the circulation of legal ideas: Protocol for a scoping review
    Paula Aguilar Peña, Fernando Muñoz León
    PLOS OnePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisPLOSPMC
  2. Buccal and sublingual lyophilised naloxone for opioid overdose reversal: A Phase 1 open-label, random-sequence crossover pharmacokinetic study protocol in healthy volunteers (NalBuc)
    Mariana Gonzalez Utrilla, Alexander Baker, Edward Chesney +3
    PLOS OnePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisPharmacology & toxicologyPhysiologyPLOSPMC
  3. Addressing unsafe abortion in India: A mixed-methods systematic review protocol
    Pratibha Dhiman, Barsha Gadapani Pathak, Subhanwita Manna +8
  4. Cost-effectiveness of recommended interventions for managing low back pain: A systematic review
    Stephanie Mathieson, Martin Underwood, Muhammad Ibrahim +10
    PLOS MedicinePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisPharmacology & toxicologyPLOSPMC
  5. Is resistance training effective to increase BDNF in multiple sclerosis? An updated systematic review and meta-analysis of isolated interventions
    William Riciere Pedon, Gustavo De Conti Teixeira Costa, Lorenzo de Ávila Rodrigues Cortizo Vidal +11
    PLOS OnePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisEpidemiology & public healthNeurologyPLOSPMC
  6. STRONG prehabilitation before elective ventral hernia repair: Learnings from recruitment challenges in a randomized controlled trial
    Sofie Anne-Marie Skovbo Jensen, Susanne Vahr Lauridsen, Siv Fonnes +4
    PLOS OnePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisEpidemiology & public healthPhysiologyPLOSPMC
  7. Machine learning and deep learning for predicting acute exacerbation in chronic obstructive pulmonary disease: a systematic review
    Qionghua Xiao, Huiru Li, Jiang Yang +3
    Systematic ReviewsPeer-reviewedCC BY 4.0Clinical trials & evidence synthesisCrossref
  8. Communication during high-stakes ICU family–clinician interactions: a realist review protocol
    Arun Ghoshal, Ashmitha Prasad, Aparna Nanda +1
    Systematic ReviewsPeer-reviewedCC BY 4.0Clinical trials & evidence synthesisCrossref
  9. Whole-course care intervention for patients with spinal cord injury: study protocol for a randomized controlled trial
    Peipei Ding, Haoran Li, Hui Huang +5
    TrialsPeer-reviewedCC BY-NC-ND 4.0Clinical trials & evidence synthesisCrossref
  10. The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial
    Pailin Intarasangkhanawin, Saritphat Orrapin, Worapong Anuponganan +2
    PLOS OnePeer-reviewedCC BYFull textClinical trials & evidence synthesisPhysiologySurgery & anaesthesiaPLOSEurope PMC
  11. Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality
    Tomohiro Takayama, Keina Sado, Kenji Suda +10
    PLOS Digital HealthPeer-reviewedCC BYFull textClinical trials & evidence synthesisPLOSEurope PMCDOAJ
  12. Personalized assistive EMG-controlled virtual reality interface combined with cerebellar-iTBS for post-stroke arm recovery (ERICA): study protocol for a three-arm randomized controlled trial
    Matteo Nocilli, Alex Martino Cinnera, Danny Adrian Spampinato +5
    TrialsPeer-reviewedCC BY-NC-ND 4.0Clinical trials & evidence synthesisCrossref
  13. Efficacy and safety of fluoroquinolones in the treatment of human brucellosis: A systematic review and meta-analysis
    Mohsen Mohammadi-Sartang, Nastaran Rafieipour, Shahla Afrasiabian +4
    PLOS Neglected Tropical DiseasesPeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisEpidemiology & public healthInfectious diseasePLOSPMC
  14. Best practices for patient authorship and involvement in pharmaceutical industry peer-reviewed publications: systematic literature review and qualitative evidence synthesis
    Adeline Rosenberg, Liz Clark, Graham R. McClelland
    Systematic ReviewsPeer-reviewedCC BY 4.0Clinical trials & evidence synthesisCrossref
  15. Assessing the robustness of meta-analyses to variability in the frequency and timing of postoperative delirium assessment – a novel methodological approach
    Maram Khaled, Harsha Shanthanna, Lehana Thabane +18
    PLOS OnePeer-reviewedCC BYFull textClinical trials & evidence synthesisPLOSEurope PMC
  16. Guidance for defining outcomes in clinical trials
    Xiangji Ying, Tianjing Li, Joanne E. McKenzie +16
    PLOS MedicinePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisPharmacology & toxicologyPLOSPMC
  17. Impact of violence on HIV outcomes among female sex workers: A global systematic review and meta-analysis
    Joshua Dawe, Khadimul Anam Mazhar, Saher Aijaz Khan +10
    PLOS MedicinePeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisEpidemiology & public healthInfectious diseasePLOSPMCDOAJ
  18. Direct and indirect entomological efficacy of Targeted Indoor Residual Spraying against Aedes aegypti in Iquitos, Peru
    Helvio Astete, Gissella M. Vasquez, Victor M. López-Sifuentes +6
    PLOS Neglected Tropical DiseasesPeer-reviewedCC0Full textClinical trials & evidence synthesisInfectious diseasePharmacology & toxicologyPLOSPMC
  19. A liquid- and capsule-compatible hydroxyurea electronic monitor to identify non-adherent youth with sickle cell disease
    Anyssa Young, Nate Goldfarb, Patrick McGann +7
    PLOS OnePeer-reviewedCC BYFull textClinical trials & evidence synthesisPLOSEurope PMC
  20. Evaluating selected gene therapies for cardiovascular diseases: an updated scoping review and evidence map of randomised controlled trials
    Eric A Apaydin, Jessica Richard, Skye A Miner +4
    Open HeartPeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisPMC
  21. Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials
    Kamil Bujak, Daniele Giacoppo, Claudio Laudani +8
    EuroInterventionPeer-reviewedLicence not statedFull text1 citedClinical trials & evidence synthesisPMC
  22. Predictors of mortality in patients with Klebsiella pneumoniae infection: a systematic review and meta-analysis
    Zhiyu Zhang, Yi Zhang, Ning Shen +2
    Systematic ReviewsPeer-reviewedCC BY 4.0Clinical trials & evidence synthesisCrossref
  23. Exploring gut microbiome dysbiosis in vasculitis in adults: a systematic review
    Kamila Hashemzadeh, Mozhdeh Ghamari, Sarah Deutsch +2
    Systematic ReviewsPeer-reviewedCC BY 4.0Full textClinical trials & evidence synthesisCrossref
  24. Effects of music intervention on improving pain in cancer patients: a protocol for systematic review of RCTs
    Soo Young Kim, Wonyoung Jung, In Sil Choi +8
    Systematic ReviewsPeer-reviewedCC BY-NC-ND 4.0Clinical trials & evidence synthesisCrossref
  25. Economic evaluation protocol of the Ntshembo (Hope) Trial (RCT) in rural and urban South Africa: an intervention to optimise adolescence body mass index (BMI) pre-conception to address the triple burden of malnutrition
    Cyril Bernsah Fonka, Dhyan Saravanja, Shane A Norris +3
    TrialsPeer-reviewedCC BY-NC-ND 4.0Clinical trials & evidence synthesisCrossref