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Peer-reviewedCC BY-NC 4.0Iranian Journal of Microbiology

Microbiological profile and antimicrobial susceptibility pattern in orthopaedic implant associated infections

  • Deepika Ilango1,2
  • Latha Ragunathan1
  • Kamalakannan Giridharan3
  • Kavitha Kannaiyan1
  • Madiha Nazer1,4
  • Bharathi Panneerselvam1,5
  • Aravind Chakkulangara Sasi6
  • Melissa Shaelyn Samuel7
7 affiliations
  1. 1Department of Microbiology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (DU), Kirumampakkam, Puducherry, India
  2. 2Department of Microbiology, Government Medical College and Hospital, Cuddalore District, Annamalai Nagar, Chidambaram, Tamilnadu, India
  3. 3Department of Orthopaedics, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (DU), Kirumampakkam, Puducherry, India
  4. 4Department of Microbiology, Sree Gokulam Medical College and Research Foundation, Kerala, India
  5. 5Department of Microbiology, Arunai Medical College and Hospital, Thiruvannamalai, Tamilnadu, India
  6. 6Department of Medical and Bioresearch, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (DU), Kirumampakkam, Puducherry, India
  7. 7Department of General Surgery, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India
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Abstract

Background and Objectives:: Postoperative wound infection is a serious complication in presence of prosthetic implantation (infectivity rate 10.4%). Implant infection is particularly high in developing countries. Hence there is a need to know the clinical presentation, common organisms and their susceptibility pattern in a particular region.

Materials and Methods:: The patients who had undergone orthopaedic prosthesis or implant surgeries and presented with signs and symptoms of infection were included in this study. Pus, tissue, fluid samples obtained were streaked in Blood agar and MacConkey agar plates and incubated at 37°C, two Sabouraud Dextrose agar slants incubated at 28°C and 37°C and Gram staining and Acid-fast staining performed. Antimicrobial susceptibility testing was performed for all bacterial isolates. Data collection was done using a proforma and analysis of data was done and expressed as frequency and percentage.

Results:: A total of 149 samples obtained from patients with Orthopaedic implant associated infections were processed. Of these 131 (87.9%) were culture positive. Staphylococcus aureus was the most common pathogen, followed by Pseudomonas spp. Escherichia coli and Staphylococcus other than S. aureus. Ten (7.6%) cases had multiple organisms and 2 fungi were also isolated (1.5%). Among the S. aureus, MSSA was the commonest and 42 (30.2%) isolates were multidrug resistant organisms.

Conclusion:: Infection is the major cause of delayed healing in patients with Orthopaedic implants. Early identification and aggressive treatment with the appropriate antibiotics are necessary to decrease infection rate, reduce hospital stay, prevent biofilm formation, decrease the need for Implant removal or replacement, and prevent disability in the patients.

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Cite

BibTeXRIS
BibTeX
@article{ilango2026microbiological,
  title = {{Microbiological profile and antimicrobial susceptibility pattern in orthopaedic implant associated infections}},
  author = {Deepika Ilango and Latha Ragunathan and Kamalakannan Giridharan and Kavitha Kannaiyan and Madiha Nazer and Bharathi Panneerselvam and Aravind Chakkulangara Sasi and Melissa Shaelyn Samuel},
  journal = {Iranian Journal of Microbiology},
  year = {2026},
  month = nov,
  doi = {10.18502/ijm.v18i5.22860},
  url = {https://doi.org/10.18502/ijm.v18i5.22860},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Microbiological profile and antimicrobial susceptibility pattern in orthopaedic implant associated infections
AU  - Deepika Ilango
AU  - Latha Ragunathan
AU  - Kamalakannan Giridharan
AU  - Kavitha Kannaiyan
AU  - Madiha Nazer
AU  - Bharathi Panneerselvam
AU  - Aravind Chakkulangara Sasi
AU  - Melissa Shaelyn Samuel
PY  - 2026
DA  - 2026/11/06
JO  - Iranian Journal of Microbiology
DO  - 10.18502/ijm.v18i5.22860
UR  - https://doi.org/10.18502/ijm.v18i5.22860
AB  - Background and Objectives:: Postoperative wound infection is a serious complication in presence of prosthetic implantation (infectivity rate 10.4%). Implant infection is particularly high in developing countries. Hence there is a need to know the clinical presentation, common organisms and their susceptibility pattern in a particular region.  Materials and Methods:: The patients who had undergone orthopaedic prosthesis or implant surgeries and presented with signs and symptoms of infection were included in this study. Pus, tissue, fluid samples obtained were streaked in Blood agar and MacConkey agar plates and incubated at 37°C, two Sabouraud Dextrose agar slants incubated at 28°C and 37°C and Gram staining and Acid-fast staining performed. Antimicrobial susceptibility testing was performed for all bacterial isolates. Data collection was done using a proforma and analysis of data was done and expressed as frequency and percentage.  Results:: A total of 149 samples obtained from patients with Orthopaedic implant associated infections were processed. Of these 131 (87.9%) were culture positive. Staphylococcus aureus was the most common pathogen, followed by Pseudomonas spp. Escherichia coli and Staphylococcus other than S. aureus. Ten (7.6%) cases had multiple organisms and 2 fungi were also isolated (1.5%). Among the S. aureus, MSSA was the commonest and 42 (30.2%) isolates were multidrug resistant organisms.  Conclusion:: Infection is the major cause of delayed healing in patients with Orthopaedic implants. Early identification and aggressive treatment with the appropriate antibiotics are necessary to decrease infection rate, reduce hospital stay, prevent biofilm formation, decrease the need for Implant removal or replacement, and prevent disability in the patients.
SN  - 2008-3289
SN  - 2008-4447
ER  -