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Peer-reviewedCC BY-NC-NDBMC neurology

Rare multi - regional involvement in posterior reversible encephalopathy syndrome with spinal cord involvement of a young hypertensive male: a case report.

  • Jingjing Dou1
  • Yuxia Li1
  • Xiangzhen Yuan1
  • Hui Zhang2
  1. 1Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.
  2. 2Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China. [email protected].
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Abstract

Background

Posterior reversible encephalopathy syndrome (PRES) is an acute or subacute cerebral syndrome which primarily manifests as headache, encephalopathy, seizures, and visual disturbances in various combinations. PRES with spinal cord involvement (PRES-SCI) is extremely rare and considered to be a variant of PRES.Case presentation

We present a case of PRES-SCI where the patient primarily manifested with bilateral blurred vision. The brain and spinal cord MRI showed that the lesions simultaneously affected the supratentorial region, infratentorial region, and spinal cord, and malignant hypertension was identified as the underlying etiology. After 8 days of blood pressure control, a follow-up MRI revealed obvious disappearance of the imaging lesions and full resolution of the blurred vision.Conclusions

Timely blood pressure management in PRES-SCI, even with extensive cerebral and spinal cord involvement, can lead to rapid symptom resolution and significant lesion reduction on imaging.

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Cite

BibTeXRIS
BibTeX
@article{dou2026rare,
  title = {{Rare multi - regional involvement in posterior reversible encephalopathy syndrome with spinal cord involvement of a young hypertensive male: a case report.}},
  author = {Jingjing Dou and Yuxia Li and Xiangzhen Yuan and Hui Zhang},
  journal = {BMC neurology},
  year = {2026},
  month = aug,
  doi = {10.1186/s12883-026-05318-1},
  url = {https://europepmc.org/article/MED/42897530},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Rare multi - regional involvement in posterior reversible encephalopathy syndrome with spinal cord involvement of a young hypertensive male: a case report.
AU  - Jingjing Dou
AU  - Yuxia Li
AU  - Xiangzhen Yuan
AU  - Hui Zhang
PY  - 2026
DA  - 2026/08/01
JO  - BMC neurology
DO  - 10.1186/s12883-026-05318-1
UR  - https://europepmc.org/article/MED/42897530
AB  - Background  Posterior reversible encephalopathy syndrome (PRES) is an acute or subacute cerebral syndrome which primarily manifests as headache, encephalopathy, seizures, and visual disturbances in various combinations. PRES with spinal cord involvement (PRES-SCI) is extremely rare and considered to be a variant of PRES.Case presentation  We present a case of PRES-SCI where the patient primarily manifested with bilateral blurred vision. The brain and spinal cord MRI showed that the lesions simultaneously affected the supratentorial region, infratentorial region, and spinal cord, and malignant hypertension was identified as the underlying etiology. After 8 days of blood pressure control, a follow-up MRI revealed obvious disappearance of the imaging lesions and full resolution of the blurred vision.Conclusions  Timely blood pressure management in PRES-SCI, even with extensive cerebral and spinal cord involvement, can lead to rapid symptom resolution and significant lesion reduction on imaging.
SN  - 1471-2377
ER  -