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Peer-reviewedCC BYClinical case reports

Pregnancy-Induced Hypertension Complicated by Posterior Reversible Encephalopathy Syndrome: A Case Series of Two Patients.

5 affiliations
  1. 1Graduate School of Bengbu Medical College Bengbu China.
  2. 2Bengbu Medical College Bengbu China.
  3. 3Department of Radiology Xuancheng People's Hospital Xuancheng China.
  4. 4Department of Obstetrics and Gynecology Hull University Teaching Hospitals NHS Trust Hull UK.
  5. 5Department of Obstetrics and Gynecology Xuancheng People's Hospital Xuancheng China.

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a rare but potentially life-threatening neurological complication associated with hypertensive disorders of pregnancy. This report presents two cases of pregnancy-induced hypertension complicated by PRES, both clinically characterized by headache and visual disturbances, with characteristic neuroimaging findings. The clinical manifestations, laboratory findings, and magnetic resonance imaging (MRI) characteristics of two patients are described. Following prompt multidisciplinary consultation and immediate interventions, including strict blood pressure control, seizure prophylaxis, infection prevention, and appropriate obstetric management, both patients achieved favorable clinical outcomes. No significant neurological abnormalities were observed at the 42-day postpartum follow-up. In patients with severe pregnancy-induced hypertension, PRES warrants recognition as a potential complication; management should prioritize rigorous blood pressure control, seizure prophylaxis, alleviation of pregnancy-related physiological stress, and timely neuroimaging to guide treatment, with strategies balancing maternal and fetal safety-early recognition and intervention underpinned by standardized protocols and multidisciplinary collaboration being critical to improving prognosis and reducing complications.

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BibTeX
@article{zhao2026pregnancyinduced,
  title = {{Pregnancy-Induced Hypertension Complicated by Posterior Reversible Encephalopathy Syndrome: A Case Series of Two Patients.}},
  author = {Xintong Zhao and Mengqing Yan and Feixiang Long and Androniks Mumdzjans and Rongrong Song},
  journal = {Clinical case reports},
  year = {2026},
  month = nov,
  doi = {10.1002/ccr3.73800},
  url = {https://europepmc.org/article/MED/42999784},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Pregnancy-Induced Hypertension Complicated by Posterior Reversible Encephalopathy Syndrome: A Case Series of Two Patients.
AU  - Xintong Zhao
AU  - Mengqing Yan
AU  - Feixiang Long
AU  - Androniks Mumdzjans
AU  - Rongrong Song
PY  - 2026
DA  - 2026/11/06
JO  - Clinical case reports
DO  - 10.1002/ccr3.73800
UR  - https://europepmc.org/article/MED/42999784
AB  - Posterior reversible encephalopathy syndrome (PRES) is a rare but potentially life-threatening neurological complication associated with hypertensive disorders of pregnancy. This report presents two cases of pregnancy-induced hypertension complicated by PRES, both clinically characterized by headache and visual disturbances, with characteristic neuroimaging findings. The clinical manifestations, laboratory findings, and magnetic resonance imaging (MRI) characteristics of two patients are described. Following prompt multidisciplinary consultation and immediate interventions, including strict blood pressure control, seizure prophylaxis, infection prevention, and appropriate obstetric management, both patients achieved favorable clinical outcomes. No significant neurological abnormalities were observed at the 42-day postpartum follow-up. In patients with severe pregnancy-induced hypertension, PRES warrants recognition as a potential complication; management should prioritize rigorous blood pressure control, seizure prophylaxis, alleviation of pregnancy-related physiological stress, and timely neuroimaging to guide treatment, with strategies balancing maternal and fetal safety-early recognition and intervention underpinned by standardized protocols and multidisciplinary collaboration being critical to improving prognosis and reducing complications.
SN  - 2050-0904
ER  -