Additively Manufactured Implants for Mandibular Overdentures: RCT Part 1 - Clinical and Peri-Implant Outcomes.
8 affiliations
- 1Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPel), Pelotas, RS, Brazil.
- 2Department of Restorative Dentistry, School of Dentistry, Federal University of Pelotas (UFPel), Pelotas, RS, Brazil.
- 3Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
- 4Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthodontics, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
- 5Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, Brazil.
- 6Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
- 7Department of Oral Health Sciences, Periodontology, KU Leuven & Dentistry, University Hospitals Leuven, Leuven, Belgium.
- 8Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Abstract
This study reported preliminary clinical outcomes of a randomized clinical trial comparing immediate and conventional loading protocols for mandibular overdentures supported by two narrow-diameter implants with a regular platform manufactured by additive technology. The focus was on primary implant stability, assessed using insertion torque and the implant stability quotient (ISQ). Sixteen completely edentulous participants (11 men, 5 women; mean age: 67.7 ± 7.6 years) received new complete dentures prior to surgery and were followed for up to 180 days, depending on the outcome assessed. Insertion torque was recorded at implant placement (motor and manual wrench), implant stability was measured at baseline and 90 days, and peri-implant healing and health parameters were evaluated at 7, 14, 30, 60, 90, and 180 days. A significance level of 5% was adopted for all statistical analyses. Immediate loading was performed on the day of implant placement, while conventional loading occurred after a 12-week healing period. The immediate loading group showed higher insertion torque (motor: 58.13 ± 5.18 Ncm, p=0.001; wrench: 58.44 ± 4.37 Ncm, p=0.004). ISQ increased significantly from baseline to 90 days in both groups (Immediate: 68.05 ± 6.08 to 72.44 ± 3.38; Conventional: 65.58 ± 5.47 to 70.72 ± 4.63; p<0.001), with no significant between-group differences (p=0.117). Peri-implant healing was more stable in the conventional group, with 100% of bone beds healed at 30 days (p=0.01). Significant between-group differences were observed at selected time points for peri-implant outcomes (p<0.05). Within the limitations of this preliminary short-term evaluation, both protocols appeared clinically feasible.
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BibTeX
@article{silva2026additively,
title = {{Additively Manufactured Implants for Mandibular Overdentures: RCT Part 1 - Clinical and Peri-Implant Outcomes.}},
author = {Lucas Jardim da Silva and Laura Lourenço Morel and Anna Paula da Rosa Possebon and Luciana de Rezende Pinto and Altair Anoninha Del Bel Cury and Jamil Awad Shibli and Otacílio Luiz Chagas Júnior and Fernanda Faot},
journal = {Brazilian dental journal},
year = {2026},
month = oct,
doi = {10.1590/0103-644020266875},
url = {https://europepmc.org/article/MED/42912074},
note = {CC BY},
}
RIS
TY - JOUR
TI - Additively Manufactured Implants for Mandibular Overdentures: RCT Part 1 - Clinical and Peri-Implant Outcomes.
AU - Lucas Jardim da Silva
AU - Laura Lourenço Morel
AU - Anna Paula da Rosa Possebon
AU - Luciana de Rezende Pinto
AU - Altair Anoninha Del Bel Cury
AU - Jamil Awad Shibli
AU - Otacílio Luiz Chagas Júnior
AU - Fernanda Faot
PY - 2026
DA - 2026/10/19
JO - Brazilian dental journal
DO - 10.1590/0103-644020266875
UR - https://europepmc.org/article/MED/42912074
AB - This study reported preliminary clinical outcomes of a randomized clinical trial comparing immediate and conventional loading protocols for mandibular overdentures supported by two narrow-diameter implants with a regular platform manufactured by additive technology. The focus was on primary implant stability, assessed using insertion torque and the implant stability quotient (ISQ). Sixteen completely edentulous participants (11 men, 5 women; mean age: 67.7 ± 7.6 years) received new complete dentures prior to surgery and were followed for up to 180 days, depending on the outcome assessed. Insertion torque was recorded at implant placement (motor and manual wrench), implant stability was measured at baseline and 90 days, and peri-implant healing and health parameters were evaluated at 7, 14, 30, 60, 90, and 180 days. A significance level of 5% was adopted for all statistical analyses. Immediate loading was performed on the day of implant placement, while conventional loading occurred after a 12-week healing period. The immediate loading group showed higher insertion torque (motor: 58.13 ± 5.18 Ncm, p=0.001; wrench: 58.44 ± 4.37 Ncm, p=0.004). ISQ increased significantly from baseline to 90 days in both groups (Immediate: 68.05 ± 6.08 to 72.44 ± 3.38; Conventional: 65.58 ± 5.47 to 70.72 ± 4.63; p<0.001), with no significant between-group differences (p=0.117). Peri-implant healing was more stable in the conventional group, with 100% of bone beds healed at 30 days (p=0.01). Significant between-group differences were observed at selected time points for peri-implant outcomes (p<0.05). Within the limitations of this preliminary short-term evaluation, both protocols appeared clinically feasible.
SN - 0103-6440
SN - 1806-4760
ER -