Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel
Abstract
Atmospheric pressure plasma jets (APPJ) have great potential in wound healing, bacterial disinfection and in cancer therapy. Recent studies pointed out that hydrogels can be used as screens during APPJ treatment, or even be used as reservoirs for reactive oxygen and nitrogen species generated by APPJ in liquids. Thus, novel applications are emerging for hydrogels which deserve fundamental exploration of the possible modifications undergone by the polymers in solution due to the reactivity with plasmas. Here we investigate the possible modifications occurred by APPJ treatment of an amphiphilic poly(ethylene oxide)-based triblock copolymer (tPEO) photo-crosslinkable hydrogel. While APPJ treatments lead to a certain degradation of the self-assembly of the polymeric chains at low concentrations (<2 g/L), at the higher concentrations required to form a hydrogel (>2 g/L), the polymeric chains are unaffected by APPJ and the hydrogel forming ability is kept. APPJ treatments induced a pre-crosslinking of the network with an increase of the mechanical properties of the hydrogel. Overall, the small modifications induced allow thinking of polymer solutions with hydrogel forming ability a new platform for several applications related to plasma medicine, and thus, with potential in different therapies.
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BibTeX
@article{hamouda2026investigating,
title = {{Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel}},
author = {Inès Hamouda and Cédric Labay and Maria Pau Ginebra and Erwan Nicol and Cristina Canal},
journal = {Polymer},
year = {2026},
month = oct,
doi = {10.1016/j.polymer.2020.122308},
url = {https://hal.science/hal-05798215v1},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel
AU - Inès Hamouda
AU - Cédric Labay
AU - Maria Pau Ginebra
AU - Erwan Nicol
AU - Cristina Canal
PY - 2026
DA - 2026/10/13
JO - Polymer
DO - 10.1016/j.polymer.2020.122308
UR - https://hal.science/hal-05798215v1
AB - Atmospheric pressure plasma jets (APPJ) have great potential in wound healing, bacterial disinfection and in cancer therapy. Recent studies pointed out that hydrogels can be used as screens during APPJ treatment, or even be used as reservoirs for reactive oxygen and nitrogen species generated by APPJ in liquids. Thus, novel applications are emerging for hydrogels which deserve fundamental exploration of the possible modifications undergone by the polymers in solution due to the reactivity with plasmas. Here we investigate the possible modifications occurred by APPJ treatment of an amphiphilic poly(ethylene oxide)-based triblock copolymer (tPEO) photo-crosslinkable hydrogel. While APPJ treatments lead to a certain degradation of the self-assembly of the polymeric chains at low concentrations (<2 g/L), at the higher concentrations required to form a hydrogel (>2 g/L), the polymeric chains are unaffected by APPJ and the hydrogel forming ability is kept. APPJ treatments induced a pre-crosslinking of the network with an increase of the mechanical properties of the hydrogel. Overall, the small modifications induced allow thinking of polymer solutions with hydrogel forming ability a new platform for several applications related to plasma medicine, and thus, with potential in different therapies.
SN - 0032-3861
ER -