Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 42 min ago
Peer-reviewedCC BYGlobal challenges (Hoboken, NJ)

Global Warming and Type 2 Diabetes: Sex and Gender as Drivers in a Multidimensional Feedback Loop.

  • Massimo D'Archivio1
  • Giulia Zanchi1
  • Alessia Tammaro1
  • Roberta Masella1
  • Claudia Cataldo1
  1. 1Gender-Specific Prevention and Health Unit Centre For Gender-Specific Medicine Istituto Superiore di Sanità Rome Italy.
Read full textPDFDOICite

Abstract

Climate change is increasingly recognized as a determinant of metabolic health. Emerging evidence indicates that rising temperatures impair glucose homeostasis-specifically through reduced brown adipose tissue activity and increased insulin resistance-thereby exacerbating type 2 diabetes mellitus (T2DM) risk. Concurrently, food systems drive substantial greenhouse gas emissions (GHGE), with gender-differentiated dietary patterns uniquely influencing both environmental impact and health outcomes. In this perspective, we move beyond well-established separate links to propose an original integrated and systemic conceptual framework. This framework connects gender-related drivers in dietary behaviors, GHGE, global warming, brown adipose tissue dysfunction, and T2DM risk into an integrated multidimensional feedback model, providing a novel basis to generate hypotheses for future mechanistic, epidemiological, and intervention studies, supporting gender-sensitive prevention strategies.

Related

  1. Protective effects of heat shock protein 70 induction against global warming by using oriental bezoar and ginseng
    E. Inoue, T. Tsubonoya, Y. Shimizu +2
    bioRxivPreprintAll rights reservedFull textPharmacology & toxicologybioRxiv
  2. Time-segmented, feedback-guided tiered warming during radical esophagectomy: a single-center retrospective cohort study
    Yanshu Liu, Jianlan Ren, Lu Xiao +5
    Frontiers in oncologyPeer-reviewedCC BYFull textOncologyEurope PMCCrossref
  3. Global warming and the National Cattlemen’s Association 1986–1996
    Jennifer Jacquet, Loredana Loy
    PLOS ClimatePeer-reviewedCC BY 4.0Full textNutritionPLOS
  4. The urgent need to adapt working conditions to global warming-driven heat waves to protect workers’ health
    Danielle Campos Bedin, João Silvestre Silva-Junior, Evangelina da Motta Pacheco Alves de Araujo
    Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMTPeer-reviewedCC BYFull textPhysiologyEurope PMCPMC
  5. Sarcopenia in type 2 diabetes mellitus: from muscle quantity to multidimensional muscle health
    Zicheng Wang, Lilu Zhu, Fangli Zhang +4
    Frontiers in EndocrinologyPeer-reviewedCC BY 4.0Full textPhysiologyCrossrefEurope PMCPMC

Cite

BibTeXRIS
BibTeX
@article{darchivio2026global,
  title = {{Global Warming and Type 2 Diabetes: Sex and Gender as Drivers in a Multidimensional Feedback Loop.}},
  author = {Massimo D'Archivio and Giulia Zanchi and Alessia Tammaro and Roberta Masella and Claudia Cataldo},
  journal = {Global challenges (Hoboken, NJ)},
  year = {2026},
  month = oct,
  doi = {10.1002/gch2.70140},
  url = {https://europepmc.org/article/MED/42898555},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Global Warming and Type 2 Diabetes: Sex and Gender as Drivers in a Multidimensional Feedback Loop.
AU  - Massimo D'Archivio
AU  - Giulia Zanchi
AU  - Alessia Tammaro
AU  - Roberta Masella
AU  - Claudia Cataldo
PY  - 2026
DA  - 2026/10/18
JO  - Global challenges (Hoboken, NJ)
DO  - 10.1002/gch2.70140
UR  - https://europepmc.org/article/MED/42898555
AB  - Climate change is increasingly recognized as a determinant of metabolic health. Emerging evidence indicates that rising temperatures impair glucose homeostasis-specifically through reduced brown adipose tissue activity and increased insulin resistance-thereby exacerbating type 2 diabetes mellitus (T2DM) risk. Concurrently, food systems drive substantial greenhouse gas emissions (GHGE), with gender-differentiated dietary patterns uniquely influencing both environmental impact and health outcomes. In this perspective, we move beyond well-established separate links to propose an original integrated and systemic conceptual framework. This framework connects gender-related drivers in dietary behaviors, GHGE, global warming, brown adipose tissue dysfunction, and T2DM risk into an integrated multidimensional feedback model, providing a novel basis to generate hypotheses for future mechanistic, epidemiological, and intervention studies, supporting gender-sensitive prevention strategies.
SN  - 2056-6646
ER  -