Pharmacology & toxicology
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- Advances in organ-on-chip for drug transporter study: Key insights and hurdles
- Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response
- Formulation and ex vivo characterization of a kaempferol transethosomal hydrogel for the prevention of UV-induced cutaneous damage
- Left to cope alone: how pregnant and postpartum women and their newborns manage extreme heat in coastal Kilifi, Kenya
- Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation
- Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning
- Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support
- Reporting signals of selected extrapyramidal adverse events with four newer second-generation antipsychotics: a disproportionality analysis of FAERS spontaneous reports
- EGFR-TKI-associated colitis in non-small cell lung cancer: a retrospective characterization of clinical, radiographic, endoscopic, and histopathologic features
- A retrospective real-world study on semaglutide effectiveness in patients with obesity: differences between patients with and without food craving
- Precision targeting of type 2 inflammation in COPD: identifying candidates for dupilumab therapy
- Impact of tropical cyclones on child marriage rates in 14 affected countries
- Gradual mitochondrial collapse underlies cytotoxicity induced by a B-type prymnesin-containing Prymnesium parvum extract in rainbow trout gill cells
- Sterol-like natural products and other secondary metabolites with antimicrobial and antiplasmodial activities from Penicillium tanzanicum
- Defining the Catalytic Boundaries of N -Nitrosourea-Forming StzF/SznF and Related Metalloenzymes through Genome Mining and Mechanistic Analysis
- Quantitative systems pharmacology modeling of class I–III BRAF-mutant NSCLC enables subgroup treatment analysis and combination therapy design
- Climate change and sexual and reproductive health: A mixed methods scoping review of possible mechanisms
- CONORM: Context-Aware Entity Normalization for Adverse Drug Event Detection
- Benzene exposure in relation to the development of glycemic dysregulation and type 2 diabetes mediated by oxidative stress and aggravated by inflammation in a repeated-measure prospective cohort study of Chinese adults
- A Multiplex Protein Microarray Platform for Preclinical Tissue Binding and Cross-Reactivity of Therapeutic Antibodies
- Dose-additive and dose-dependent fetal testis toxicity of a nine-phthalate mixture in the rat
- Arsenic Impairs Critical Cellular Events of Human Cardiac Development Across Differentiation and Metabolic Maturation
- Multi-Platform Metabolomic and Sensory Profiling Reveals Cultivar-Dependent Volatile, Taste, and Antioxidant Chemotypes in Guava Leaf Tea.
- Comparative Effectiveness of Aquatic Versus Land-Based Exercise on Pain, Physical Function, and Quality of Life in People with Knee Osteoarthritis: An Updated Systematic Review of Randomised Controlled Trials.
- Performance of the Heatwave ED Forecast Tool in the Emergency Department Network of Ticino Canton, Switzerland